Protein Alignment ArfGAP3 and appl1

DIOPT Version :9

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_021335332.1
• Gene: appl1 / 571540
• ZFINID: ZDB-GENE-081016-1
• Length: 708
• Species: Danio rerio
• Alignment Length: 415
• Identity: 84/415 - (20%)
• Similarity: 136/415 - (32%)
• Gaps: 131/415 - (31%)

  Fly   105 AQVKYNSRAAQLYRDKLCAQAQQAMKTHGTKLHLEQTDKSEGNEAAREEDFFAQCDNEV--DFNV 167
            ||:.:    .:|..:.|..|.:..:...||.:          ....||.|..|:...:.  |...
Zfish   206 AQISF----FKLGSENLTQQWEDFLTNIGTSV----------QNVRREMDSDAEAMEQTIQDLKE 256

  Fly   168 QNNNVSKQDPNPPTVAPVISVETQQGGAPSVNLLNSVVPAAVPSSIGARKVQPKKGG------LG 226
            .::.:...||:|..: ||....|::.|     .||:.....:.||...|:....:||      .|
Zfish   257 ASDPLYMPDPDPNRI-PVNRNLTRKAG-----YLNTRNKTGLVSSSWERQYFFTQGGNLMSQSRG 315

  Fly   227 ARKVGGL--GATKVKTNFADIEARANAANEMKTSAAAAPVVKPQTAEDELETVASMRLAYQELSM 289
            | ..|||  ..........|.|.|.............|.|::..:.:|..|.:|::....:.:.:
Zfish   316 A-VAGGLVMDIDNCSVMAVDCEDRRFCFQITAFDGKKAAVLQADSRKDCEEWIATINNISKRIYL 379

  Fly   290 QKTREE-------AKLKTMDPAKAKQMERLGMGFNLRGSDMAHSALGDMETIQQSAAPKAKLSLL 347
            .:..||       :.|:.:.|:.:.|...                    |:.:.:...|.|.
Zfish   380 SENPEEIAARVNQSALEAVTPSPSFQQRH--------------------ESFRPNTQGKVKA--- 421

  Fly   348 ESENFFTDFSLYGNSSSGGGGGGSSEKRESSVGGTS-KLDKFELDAL-------GYETIEPIGGS 404
                          |.||.         :.|||..| .|....||:|       .::.|.|:...
Zfish   422 --------------SRSGS---------QCSVGSESPALSSLSLDSLVAPDTPIQFDIISPVSEE 463

  Fly   405 HSNITSMFSRSNDYDKPKTSAPVKKNSGSSQTHTKGGTSTDPVIAQQKFGNSKGFGSDQYFASEQ 469
            |::.|            |:||.              |..|:|      ||.|.|..|::   ||.
Zfish   464 HTSQT------------KSSAQ--------------GRRTNP------FGESGGSQSEE---SED 493

  Fly   470 SSADVSASLNRFQGS---RAISSSD 491
            |... ...:.||.||   :|..|||
Zfish   494 SILH-QLFIVRFLGSMEVKATESSD 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	3/15 (20%)
appl1	XP_021335332.1	BAR_APPL1	20..234	CDD:153315	7/41 (17%)
		BAR-PH_APPL	252..376	CDD:270067	28/130 (22%)
		PTB_APPL	488..623	CDD:269980	12/34 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900