DRSC/TRiP Functional Genomics Resources

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Protein Alignment ArfGAP3 and acap2a

DIOPT Version :9

Sequence 1:NP_001097664.2 Gene:ArfGAP3 / 40487 FlyBaseID:FBgn0037182 Length:553 Species:Drosophila melanogaster
Sequence 2:XP_005163306.1 Gene:acap2a / 564814 ZFINID:ZDB-GENE-081104-34 Length:824 Species:Danio rerio


Alignment Length:323 Identity:78/323 - (24%)
Similarity:118/323 - (36%) Gaps:99/323 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 ESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTNLDTNWTWL 78
            ||...|:.|.|.|:.|.||....|.|:|:...|.:||:||.:||:||||.:.|||..||| |...
Zfish   402 ESALQRVLAIPGNEFCCDCGQSDPRWASINLCITLCIECSGIHRSLGVHNSKVRSLTLDT-WEPE 465

  Fly    79 QLRQMQLGGNANAAQFFRAH-------NCSTTDAQVKYNSRAAQLYRDK---LCAQAQQAMKTHG 133
            .|:.|...||....|.:.||       .....|.:.:..:.....|.||   |....|:.|:...
Zfish   466 LLKLMCELGNDVINQIYEAHREENGGKKPQPGDPRREIEAFIRAKYVDKRFVLKPTEQEQMEKIM 530

  Fly   134 TKLHLEQTDK-SEGN----------------------------EAAREEDFFAQCDNEVD----- 164
            |   |.:.|| .:||                            :..|.:..|  |.:|:|     
Zfish   531 T---LRKHDKRMQGNMEFLPPRPPPPTPKLRTASNASVASLSGQEVRRDSLF--CPDELDSLFSY 590

  Fly   165 FNVQN--NNVSKQDPNPPTVAPVISVETQQGGAPSVNLLNSVVPAAVPSSIGARKVQPKKGGLGA 227
            |:..:  .|:.:.|..           .|.....|..:|     |:.|||               
Zfish   591 FDTSSKLQNLKRADSG-----------IQNSADGSREML-----ASTPSS--------------- 624

  Fly   228 RKVGGLGATKVKTNFADIEARANAANEMKTSAAAAPVVKPQT--AEDELETVASMRLAYQELS 288
                   ::..:|:..:.||.||.|..       :||....|  :.|.|...||...:.::::
Zfish   625 -------SSLSETDLPESEAAANQAER-------SPVFSKLTNFSADSLLYWASCACSLKDMA 673

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ArfGAP3NP_001097664.2 ArfGap 17..121 CDD:214518 39/113 (35%)
acap2aXP_005163306.1 BAR_ACAP2 18..217 CDD:153322
PH_ACAP 273..369 CDD:270070
PH 273..365 CDD:278594
ArfGap 402..520 CDD:279720 42/118 (36%)
ANK repeat 657..686 CDD:293786 4/17 (24%)
ANK 658..776 CDD:238125 3/16 (19%)
Ank_2 660..754 CDD:289560 2/14 (14%)
ANK repeat 690..721 CDD:293786
ANK repeat 723..754 CDD:293786
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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