DRSC/TRiP Functional Genomics Resources

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Protein Alignment ArfGAP3 and ADAP2

DIOPT Version :9

Sequence 1:NP_001097664.2 Gene:ArfGAP3 / 40487 FlyBaseID:FBgn0037182 Length:553 Species:Drosophila melanogaster
Sequence 2:XP_024306599.1 Gene:ADAP2 / 55803 HGNCID:16487 Length:403 Species:Homo sapiens


Alignment Length:169 Identity:44/169 - (26%)
Similarity:64/169 - (37%) Gaps:42/169 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 GPSKQEIESVFSRLRA-QPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTN 70
            |..::..:.:...||| ...|..|.||.|..|.|:|...|||||::|..||||. ..::.|:|..
Human     2 GDRERNKKRLLELLRAPDTGNAHCADCGAADPDWASYKLGIFICLNCCGVHRNF-PDISRVKSVR 65

  Fly    71 LDTNWTWLQLRQMQLGGN--------ANAAQFF---RAHNCSTTDAQ---VKYNSRA-------- 113
            ||. |....:..|...||        |....|:   :|::|.....|   .||..|.        
Human    66 LDF-WDDSIVEFMIHNGNLRVKAKFEARVPAFYYIPQANDCLVLKEQWIRAKYERREFMADGETI 129

  Fly   114 -----------------AQLYRDKLCAQAQQAMKTHGTK 135
                             :|..|.|....|::.:..:.||
Human   130 SLPGNREGFLWKRGRDNSQFLRRKFVLLAREGLLKYFTK 168

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ArfGAP3NP_001097664.2 ArfGap 17..121 CDD:214518 39/143 (27%)
ADAP2XP_024306599.1 ArfGap 8..126 CDD:307528 37/119 (31%)
PH1_ADAP 133..241 CDD:270072 6/36 (17%)
PH2_ADAP 255..362 CDD:241282
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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