Protein Alignment ArfGAP3 and Arfgap3

DIOPT Version :10

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_063120224.1
• Gene: Arfgap3 / 503165
• RGDID: 1560066
• Length: 536
• Species: Rattus norvegicus
• Alignment Length: 566
• Identity: 218/566 - (38%)
• Similarity: 300/566 - (53%)
• Gaps: 74/566 - (13%)

  Fly     8 PSKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTNLD 72
            ||||:|.::|.|||:.|.||.||||.||.|:|:|::||:|:|||||..||:|||||:|:|||.||
  Rat     4 PSKQDILAIFKRLRSVPTNKVCFDCGAKNPSWASISYGVFLCIDCSGSHRSLGVHLSFIRSTELD 68

  Fly    73 TNWTWLQLRQMQLGGNANAAQFFRAHNCSTTDAQVKYNSRAAQLYRDKLCAQAQQAMKTHGTKLH 137
            :||:|.|||.||:||||||:.||..|.|:|.|...|||||||||||:|:...|.||.:.|||.|.
  Rat    69 SNWSWFQLRCMQVGGNANASSFFHQHGCATKDTNAKYNSRAAQLYREKIKTLATQATRRHGTDLW 133

  Fly   138 LEQTDKSEGNEAAREEDFFAQCDNEVDFNVQNNNVSKQDPNPPTVAP---VISVETQQGG---AP 196
            |:.......:...:||||||   :.....|.....:...|.|.:..|   ..:.|..:||   .|
  Rat   134 LDSCAAPPASPPPKEEDFFA---SHASLEVSGATQASAQPEPASSTPWGLETTPEKHEGGPGQGP 195

  Fly   197 SVNLLNS---VVPAAVPSSIGARKVQPKKGGLGARKVGGLGATKV-KTNFADIEARANAANEMKT 257
            ||..||:   ..||.|.|.|..:..|.|| ||||:| |.|||.|: .|:|.:||.:|.|.::.|.
  Rat   196 SVEGLNTPGKTAPAEVSSIIKKKPNQAKK-GLGAKK-GSLGAQKLTNTSFTEIEKQAQAVDKRKE 258

  Fly   258 SAAAAPVVKPQTAEDELETVASMRLAYQELSMQKTREEAKLKTMDPAKAKQMERLGMGFNLRGSD 322
            ....|     :....|...|:|:||||::|.:.|.::| :|......|| :.|||||||......
  Rat   259 QEDLA-----RGTPKEESIVSSLRLAYKDLEIHKKQDE-RLNLSGQKKA-EAERLGMGFGSCRGG 316

  Fly   323 MAHSALGDMETIQQS----AAPKAKLSLLESENFFTDFSLYGNSSSGGGGGGSSEKRESSVGGTS 383
            ::||...||:||:|.    |.|:.|......:::|:..|.:...||                  |
  Rat   317 ISHSVTSDMQTIEQESPTLAKPRRKYQEDPEDSYFSSSSKWSEQSS------------------S 363

  Fly   384 KL--DKFELDALGYETIEPIGGSHSNITSMFSRSNDY---DKPKTSAPVKKNSGSS-QTHTKGGT 442
            :.  |..||.:             |:.:|....::.|   |..:...|..|::||| :..::...
  Rat   364 RYFDDPMELRS-------------SHFSSWDDSADSYWKKDSSRDPEPATKSTGSSDRPSSRRKP 415

  Fly   443 STDPV----IAQQKFGNSKGFGSDQYFA-SEQSSADVSASLNRFQGSRAISSSDYFGDGSPGGTG 502
            ..:||    .||:||||.|...||.||. ..|:..:..|.|.|...|.:|||:|.|.:.....||
  Rat   416 EYEPVGNTDEAQKKFGNVKAISSDMYFGIQSQTDFETRARLERLSTSSSISSADLFDEQRKQTTG 480

  Fly   503 GNRASSVNFSAPDLDVESVKESVRQGVHKVAGRLSNLANDVMTSWQ 548
            ....|:|..:|||:      ...:|||..|||:||..||.||||.|
  Rat   481 NYNLSNVLPNAPDM------AQFKQGVRSVAGKLSVFANGVMTSIQ 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap_ArfGap2_3_like	12..127	CDD:350060	71/114 (62%)
Arfgap3	XP_063120224.1	None