Protein Alignment ArfGAP3 and ArfGAP1

DIOPT Version :10

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_524040.2
• Gene: ArfGAP1 / 39417
• FlyBaseID: FBgn0020655
• Length: 468
• Species: Drosophila melanogaster
• Alignment Length: 571
• Identity: 139/571 - (24%)
• Similarity: 207/571 - (36%)
• Gaps: 176/571 - (30%)

  Fly     1 MASPAAGPSKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTF 65
            ||||       ....|...|:.|..|..||:|....|.|.||||||:||::||..||:|||||:|
  Fly     1 MASP-------RTRRVLQELKPQDENSKCFECGTHNPQWVSVTYGIWICLECSGKHRSLGVHLSF 58

  Fly    66 VRSTNLDTNWTWLQLRQMQLGGNANAAQFFRAHNCSTTDAQV--KYNSRAAQLYRDKLCAQAQQA 128
            |||..:| .|..::|.:|:.|||.||.:|..........|.:  :|||:||.|||||:...||
  Fly    59 VRSVTMD-KWKDIELEKMKAGGNRNAREFLEDQEDWNERAPITQRYNSKAAALYRDKIATLAQ-- 120

  Fly   129 MKTHGTKLHLEQTDKSEGNEAAREEDFFAQCDNEVDFNVQNNNVSKQDPNPPTVAPVISVETQQG 193
                |....|::.....|:            :|.......:|:..:..|:          .|..|
  Fly   121 ----GKSWDLKEAQGRVGS------------NNSFSSGGSSNSSYQSRPS----------ATGYG 159

  Fly   194 GAPSVNLLNSVVPAA---------------------VPSSIGARKVQPKKGGLGARKVGGLGATK 237
            |...........|..                     |.::.....:.|.:||    |..|.|.|:
  Fly   160 GNGGYQNGGGAEPGGYQQYQTQEFKDQKEEFFSRRQVENASRPENLPPSQGG----KYAGFGFTR 220

  Fly   238 ---VKTNFAD-----IEARANAANEMKTSAAAAPVVKPQTAEDELETVASMRLAYQELSMQKTRE 294
               .||...:     :...|:..:...|:|:..    ..||:::..|..:       |:..|.:|
  Fly   221 EPPPKTQSQELFDSTLSTLASGWSLFSTNASKL----ASTAKEKAVTTVN-------LASTKIKE 274

  Fly   295 EAKLKTMD------PAKAKQMERLGMGFNLRGSDMAHSALGDMETIQQSAAPKAKLSLLESENFF 353
            ...|.::.      .:|...|.:.|.. ||.||:::....|                  .::..|
  Fly   275 GTLLDSVQCGVTDVASKVTDMGKRGWN-NLAGSNISSPQGG------------------YNDPNF 320

  Fly   354 TDFSLYGNSSSGGGG-----GGSSEKRESSVGGTSKLDKFELDALGYETIEPIGGSHSNITSMFS 413
            .|.|.|..|:|.||.     |..|...:|..||.                :..|.|.|::||..|
  Fly   321 EDSSAYQRSNSVGGNLAGGLGQQSGVSDSDWGGW----------------QDNGNSKSHMTSSSS 369

  Fly   414 RSNDYDKPKTSAPVKKNSGSSQTHTKGGTSTDPVIAQQKFGNSKGFGSDQYFASEQSSADVSASL 478
            ..|.         :..:||       |||:            |.|...|         ||.|.
  Fly   370 YHNQ---------LSSSSG-------GGTA------------SAGLTRD---------ADWSG-- 395

  Fly   479 NRFQGSRAISSSDYFGDGSPGGTGGNR-------ASSVNFSAPDLDVESVK 522
              |:.:...||...:.:.|.||:...|       :..::.....|||:|||
  Fly   396 --FEATNYQSSETSYQNASSGGSTARRNMKLQDTSQKLSEGFESLDVKSVK 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap_ArfGap2_3_like	12..127	CDD:350060	52/116 (45%)
ArfGAP1	NP_524040.2	ArfGap_ArfGap1	6..121	CDD:350059	53/121 (44%)