Protein Alignment ArfGAP3 and Agfg1

DIOPT Version :9

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001129068.1
• Gene: Agfg1 / 363266
• RGDID: 1560041
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 129/613 - (21%)
• Similarity: 205/613 - (33%)
• Gaps: 163/613 - (26%)

  Fly     5 AAGPSKQEIESVFSRLR---AQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLG-VHLTF 65
            ||...:::.|.....||   ..|.|:.||||..:.||:.::|.|.|:|..||...|.|. .|.
  Rat     2 AASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHR-- 64

  Fly    66 VRSTNLDTNWTWLQLRQMQLGGN--------------ANAAQFFRAHNCSTTDAQVKYNSR---- 112
            |:|.:: |.:|..::..:|..||              ::|...||.........|.||..:
  Rat    65 VKSISM-TTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYV 128

  Fly   113 -------AAQLYRDKLCAQAQQAMKTHGTK------------LHLEQ--------TDKSEGNEAA 150
                   .|.::.....:.|.....|...|            |||.:        ..:|:|.:..
  Rat   129 PPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGESAPALHLNKGTPTQSPVVGRSQGQQQE 193

  Fly   151 REE---------DFFA-------QCDNEVDFNVQNNNVSKQDPNPPTVAPVISVETQQGGAPSVN 199
            :::         |.||       ...|..:|...|::.::...|    |...:.:.....:.|.|
  Rat   194 KKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSAN----AEFANFDAFGQSSGSSN 254

  Fly   200 LLNSVVPAAVPSSIGARKVQPKKGGLGARKVGGLGATKVKTNFADIEARANAANEMKTSAAAAPV 264
            .  ...|.|..|..     ||:..|      |..|:  |..|||..:      |..|:|:|....
  Rat   255 F--GGFPTASHSPF-----QPQTTG------GSAGS--VNANFAHFD------NFPKSSSADFGS 298

  Fly   265 VKPQTAEDELETVASMRLAYQELSMQKTREEAKLKTMDPA-KAKQMERLGMGFNLRG-------- 320
            .....:.....||:  :::..:..:|...:.|.|..:|.. .|.|....|.||...|
  Rat   299 FSTSQSHQTASTVS--KVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVV 361

  Fly   321 --------SDMAHSALGDMETIQQSAAPKAKLSLLESENFFTDFSLYGNSSSGGGG----GGSSE 373
                    |...::||.:::::..|||        .|.|.:|..|   |:||...|    |.|.:
  Rat   362 SVPSHSSASSDKYAALAELDSVFSSAA--------TSNNAYTSTS---NASSSVFGTVPVGASPQ 415

  Fly   374 KRESSVG--------------------GTSKLDKFELDALGYETIEPIGGSHSNITSMFSRSNDY 418
            .:.:|.|                    ..|..:.|:.:|.| .|....|.:..::.:.|.....|
  Rat   416 TQPASSGPAPFGATPSTNPFVAATGPSAASSTNPFQTNARG-ATAATFGTASMSMPAGFGTPAQY 479

  Fly   419 DKPKTSAPVKKNSGSSQTHTKGGTSTDPVIAQQKFGNSKGFGSDQYFASEQSSADVSASLNRF-Q 482
            ..|              |...|.....|..||..|.....|......|...:.......:..| |
  Rat   480 SLP--------------TSFSGSFQQPPFPAQAAFPQQTAFSQQPNGAGFATFGQTKPVVTPFGQ 530

  Fly   483 GSRAISSSDYFGDGSPGGTGGNRASSVN 510
            .:.|..||:.|..|:|.|.....:||.|
  Rat   531 VAAAGVSSNPFMTGAPTGQFPTGSSSTN 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	33/132 (25%)
Agfg1	NP_001129068.1	COG5347	8..309	CDD:227651	68/328 (21%)
		ArfGap	14..135	CDD:214518	32/123 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..193		5/21 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	409..451		5/41 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900