Protein Alignment ArfGAP3 and Agfg2

DIOPT Version :9

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_006249202.1
• Gene: Agfg2 / 304375
• RGDID: 1306590
• Length: 488
• Species: Rattus norvegicus
• Alignment Length: 565
• Identity: 117/565 - (20%)
• Similarity: 172/565 - (30%)
• Gaps: 192/565 - (33%)

  Fly     2 ASPAAGP------SKQEIESVFS----RLR-----AQPANKSCFDCAAKAPTWSSVTYGIFICID 51
            |....||      ||.|.|:...    |:|     :|..|:.||:||.:..|:..:|.|.|:|..
  Rat     5 AKKGPGPGGGVAGSKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDITVGSFVCTT 69

  Fly    52 CSAVHRNLG-VHLTFVRSTNLDTNWTWLQLRQMQLGGNANAAQFFRAHNCSTTDAQVKYNSRAAQ 115
            ||.:.|.|. .|.  |:|.:: |.:|..::..:|..||
  Rat    70 CSGLLRGLNPPHR--VKSISM-TTFTEPEVLFLQSRGN--------------------------- 104

  Fly   116 LYRDKLCAQAQQAMKTHGTKLHLEQTDKSEGNEAARE----EDFFAQCDNEVDFNVQNNNVSKQD 176
                ::|.:....:....|.|..:..|..:..|..:|    :.::...:     .|:..:.||..
  Rat   105 ----EVCRKIWLGLFDARTSLVPDSRDPQKVKEFLQEKYEKKRWYVPPE-----QVKGASYSKGS 160

  Fly   177 PNPPTVAPVISVETQQG----GAPSVNLLNSVVP----AAVPSSIGARKVQPKKGGLGARKVGGL 233
                     :|....||    |.|...||...||    ||..||....:.|.:.....:.:....
  Rat   161 ---------VSATPVQGSVPEGKPIRTLLGDPVPSLSDAASTSSQSVSQSQARTAQARSSQPPSH 216

  Fly   234 GATKVKTNFADIEARANAANEMKTSAAAAPVVKPQTAEDELETVASMRLAYQELSMQKTREEAKL 298
            .:||            .|:.::.......|...||.|    ...||.
  Rat   217 SSTK------------KASTDLLADIGGDPFAAPQVA----PAFASF------------------ 247

  Fly   299 KTMDPAKAKQMERLG--MGFNLRGSDMAHSALGDM-----ETIQQSAAPKAKLSLLESENFFTDF 356
                |....|....|  ..|:...|..:.||.|.:     ...|....|.|...|..|.:|
  Rat   248 ----PGFGGQNPSHGGFANFDAFSSSPSSSAFGSLPPSVQTPFQAQPTPAANRMLTGSYSF---- 304

  Fly   357 SLYGNSSSGGGG-----GGSSEKRESSVGGTSKLDKFELDALGYETIEP---IGGSHSNITSMFS 413
               |:|.....|     ..|.....:.|||               .:||   .||...::..|.|
  Rat   305 ---GSSQMSAFGVAPLAAASQPNSLADVGG---------------LLEPRMAAGGLPGSVFGMPS 351

  Fly   414 RSNDYDKPKTSAPVKKNSGSSQTHTKGGTSTDPVI--AQQKFGNSKGFGSDQYFASEQSSADVSA 476
            :     .|...:.|....||  |....|..|:|..  ||.:.                      .
  Rat   352 Q-----VPALQSAVPGVGGS--TGLPFGAFTNPFTTPAQPQL----------------------P 387

  Fly   477 SLNRFQGSRAISSSDYFGDGS-------PGGTGGNRASSVNFSAP 514
            |.|.|| ...|:|...:|.||       |....|..||:  |.||
  Rat   388 STNPFQ-PNGIASGPGYGMGSVQPGLLQPAPPSGAFAST--FPAP 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	25/113 (22%)
Agfg2	XP_006249202.1	ArfGap	40..152	CDD:295313	29/150 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900