DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ArfGAP3 and Adap1

DIOPT Version :9

Sequence 1:	NP_001097664.2	Gene:	ArfGAP3 / 40487	FlyBaseID:	FBgn0037182	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	NP_766311.2	Gene:	Adap1 / 231821	MGIID:	2442201	Length:	374	Species:	Mus musculus

Alignment Length:	244	Identity:	60/244 - (24%)
Similarity:	95/244 - (38%)	Gaps:	50/244 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 AGPSKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTN 70
            ||..::.:..:.:|    |.|..|.||.|..|.|:|.|.|:|||:.||.:|||: ..::.|:|..
Mouse     2 AGERRRALLELLTR----PGNTRCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVR 61

  Fly    71 LDTNWTWLQLRQMQLGGNANAAQFFRA------HNCSTTDAQVKYNS--RAAQLYRDKLCAQAQQ 127
            ||. |...|:..|...||..|...|.:      :..:.:|.|:....  ||....::.:..:.|:
Mouse    62 LDA-WDEAQVEFMASHGNEAARATFESKVPPFYYRPTFSDCQLLREQWIRAKYERQEFVHVEKQE 125

  Fly   128 AMKTHGTKLHLEQTDKSEGNEAAREEDFFAQCDNEVDFNVQNNNVSKQDPNPPTVAPVISVETQQ 192
            ...|...:..|.:..:..|...:|:   |...:.|......|.|.:|:   |..|.
Mouse   126 PYSTGYREGLLWKRGRDNGQFLSRK---FVLTEREGALKYFNKNDAKE---PKAVM--------- 175

  Fly   193 GGAPSVNLLNSVVPAAVPSSIGARKVQPKKGGLGARKVGGLGATKVKTN 241
                .:..||:.             .||.|.|    ...||..|.:|.|
Mouse   176 ----KIEHLNAT-------------FQPAKMG----HPHGLQVTYLKDN 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	35/111 (32%)
Adap1	NP_766311.2	ArfGap	10..126	CDD:214518	36/121 (30%)
		PH1_ADAP	130..238	CDD:270072	21/110 (19%)
		PH2_ADAP	252..357	CDD:241282
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810