Protein Alignment ArfGAP3 and Agfg2

DIOPT Version :9

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001290195.1
• Gene: Agfg2 / 231801
• MGIID: 2443267
• Length: 490
• Species: Mus musculus
• Alignment Length: 535
• Identity: 114/535 - (21%)
• Similarity: 170/535 - (31%)
• Gaps: 177/535 - (33%)

  Fly     7 GPSKQEIESVFS----RLR-----AQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLG-V 61
            |.||.|.|:...    |:|     :|..|:.||:||.:..|:..:|.|.|:|..||.:.|.|. .
Mouse    16 GGSKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPP 80

  Fly    62 HLTFVRSTNLDTNWTWLQLRQMQLGGNANAAQFFRAHNCSTTDAQVKYNSRAAQLYRDKLCAQAQ 126
            |.  |:|.:: |.:|..::..:|..||                               ::|.:..
Mouse    81 HR--VKSISM-TTFTEPEVLFLQSRGN-------------------------------EVCRKIW 111

  Fly   127 QAMKTHGTKLHLEQTDKSEGNEAAREEDFFAQCDNEVDFNVQNNNVSKQDPNPPTVAP-VISVET 190
            ..:....|.|..:..|..:..|..:|:           :..:...|..:....|:.:. .:|...
Mouse   112 LGLFDARTSLIPDSRDPQKVKEFLQEK-----------YEKKRWYVPPEQVKGPSYSKGSVSATP 165

  Fly   191 QQG----GAPSVNLLNSVVP---------------AAVPSSIGARKVQP------KK-------- 222
            .||    |.|...||...||               :...||..||..||      ||
Mouse   166 VQGSVPEGKPIRTLLGDPVPSLSDPASTSSQPGSQSQARSSSQARSSQPPSHSSTKKASTDLLAD 230

  Fly   223 -GG--LGARKV---------GGLGATKVKTNFADIEARANAANEMKTSAAAAPVVKPQTAEDELE 275
             ||  ..|.:|         .|:|.|.....||:.:|.:::.:.....:....|..|..|:   .
Mouse   231 IGGDPFAAPQVVPAFASFPGFGVGQTPAHGGFANFDAFSSSPSSSTFGSLPPSVQAPFQAQ---P 292

  Fly   276 TVASMRLAYQELSMQKTREEAKLKTMDPAKAKQMERLG-----MGFNLRGSDMAHSALGDMETIQ 335
            |.|:.|:.....|....:..| ......|.|.|...|.     :|..:....:..|..|....:.
Mouse   293 TPAANRMLTGSYSFGSGQMSA-FGVAPLAAASQPNNLADVGGLLGPRMAAGGLPGSVFGMPSQVP 356

  Fly   336 --QSAAPKAKLS------------------LLESENFFTDFSLYGNSSSGGGGGGSS-------- 372
              |||.|....|                  .|.|.|.|....|    :||.|.|.||
Mouse   357 ALQSAVPGVSGSGGLPFGAYTNPFATPAQAQLPSTNPFQPNGL----ASGPGFGMSSVRPGLLQP 417

  Fly   373 ------------------------EKRESSVG--GTSKLDKFELDALGYETIEPIGGSHSNITSM 411
                                    ::..||.|  |||||.:..|.       :|.|.|.:..  |
Mouse   418 VPPSGAFASPFSAPVFPTQAGLADQQNGSSFGDLGTSKLGQRPLS-------QPAGISTNPF--M 473

  Fly   412 FSRSNDYDKPKTSAP 426
            ...|....||.|:.|
Mouse   474 TGSSAFASKPPTTNP 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	25/113 (22%)
Agfg2	NP_001290195.1	ArfGap	40..152	CDD:295313	30/156 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900