Protein Alignment ArfGAP3 and Arfgap1

DIOPT Version :9

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_001361599.1
• Gene: Arfgap1 / 228998
• MGIID: 2183559
• Length: 424
• Species: Mus musculus
• Alignment Length: 541
• Identity: 131/541 - (24%)
• Similarity: 193/541 - (35%)
• Gaps: 156/541 - (28%)

  Fly     1 MASPAAGPSKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTF 65
            ||||       ....|...:|||..|..||:|.|..|.|.||||||:||::||..||.|||||:|
Mouse     1 MASP-------RTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSF 58

  Fly    66 VRSTNLDTNWTWLQLRQMQLGGNANAAQFFRAHNC--STTDAQVKYNSRAAQLYRDKLCAQAQQA 128
            |||..:| .|..::|.:|:.||||...:|....:.  .:...|.||:||||.|:|||:...|
Mouse    59 VRSVTMD-KWKDIELEKMKAGGNAKFREFLETQDDYEPSWSLQDKYSSRAAALFRDKVATLA--- 119

  Fly   129 MKTHGTKLHLEQTDKSEGNEAAREEDFFAQCDNEVDFNVQNNNVSKQDPNPPTV---APVISVET 190
                            ||.|.:.|..           ..||    ...|.|.|:   |...|.:.
Mouse   120 ----------------EGKEWSLESS-----------PAQN----WTPPQPKTLQFTAHRASGQP 153

  Fly   191 QQGGAPSVNLLNSVVPAAVPSSIGARKVQPKKGGLGARKVGGLGATKVKTNFADIEARANAANEM 255
            |...|.........:...:.|..||::          .:..|.|.|
Mouse   154 QSAAASGDKAFEDWLNDDLGSYQGAQE----------NRYVGFGNT------------------- 189

  Fly   256 KTSAAAAPVVKPQTAEDEL--ETVASMRLAYQELSMQKTREEAKLKTMDPAKAKQMERLGMGFNL 318
                     |.||..||:.  ..::|:...:...:...::..:..|........|..:...|:..
Mouse   190 ---------VPPQKREDDFLNNAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKFWGYKQ 245

  Fly   319 R---GSDMAHSALGDMETIQQSAAPKAKLSLLESENFFTDFSLYGNSSSGGGGGGSSEKRESSVG 380
            :   .|::.||.   .|.:.:.|..|.|     ....|.|.|           .|.|:......|
Mouse   246 QSEPASELGHSL---NENVLKPAQEKVK-----EGRIFDDVS-----------SGVSQLASKVQG 291

  Fly   381 GTSKLDKFELDALGYETIEPIGGSHSNITSMFS--RSNDYDKPKTSAPVKKNSGSSQTHTKGGTS 443
            ..||         |:.          ::|:.||  ..:..|:|.        .|.|..::.|..|
Mouse   292 VGSK---------GWR----------DVTTFFSGKAEDSSDRPL--------EGHSYQNSSGDNS 329

  Fly   444 TDPVIAQQKFGNSKGFGSDQYFASEQSSADVSASLNRFQGSRAISSSDYFGDGS----------- 497
            .:..| .|.|..:  |||.:...::..|:|.....:...|.|:..|.|.:|.||
Mouse   330 QNSNI-DQSFWET--FGSAEPPKAKSPSSDSWTCADASTGRRSSDSWDVWGSGSASNNKNSNSDG 391

  Fly   498 ----PGGTGGNRASSVNFSAP 514
                .|.:|..||.:...:||
Mouse   392 WESWEGASGEGRAKATKKAAP 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	50/105 (48%)
Arfgap1	NP_001361599.1	ArfGap_ArfGap1	6..121	CDD:350059	53/134 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810