Sequence 1: | NP_001097664.2 | Gene: | ArfGAP3 / 40487 | FlyBaseID: | FBgn0037182 | Length: | 553 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_722483.2 | Gene: | Acap1 / 216859 | MGIID: | 2388270 | Length: | 740 | Species: | Mus musculus |
Alignment Length: | 360 | Identity: | 77/360 - (21%) |
---|---|---|---|
Similarity: | 125/360 - (34%) | Gaps: | 85/360 - (23%) |
- Green bases have known domain annotations that are detailed below.
Fly 5 AAGPSKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRST 69
Fly 70 NLDTNWTWLQLRQMQLGGNANAAQFFRAH-----------NCSTTDAQVKYNSRAAQLYRDKLCA 123
Fly 124 QAQQAMKTHGTKLHLEQTDKSEGNEAAR-----------------------------EEDFFAQC 159
Fly 160 DNEVDFNVQNNNVSKQDPNPPTVAPVIS-------VETQQGGAPSV---NLLNSVVPAAVPSSIG 214
Fly 215 ARKVQPKKGGLG----ARKVG--GLGATKVKTNFADIEARANAANEMKTSA---AAAPVVKPQTA 270
Fly 271 EDELETVASMRLAYQELSMQKTREEAKLKTMDPAK 305 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
ArfGAP3 | NP_001097664.2 | ArfGap | 17..121 | CDD:214518 | 32/114 (28%) |
Acap1 | NP_722483.2 | Required for formation of endosomal tubules when overexpressed with PIP5K1C. /evidence=ECO:0000250|UniProtKB:Q15027 | 1..382 | ||
BAR_ACAP1 | 18..217 | CDD:153323 | |||
PH | 266..360 | CDD:278594 | |||
PH_ACAP | 268..364 | CDD:270070 | |||
Required for interaction with GULP1. /evidence=ECO:0000250|UniProtKB:Q15027 | 405..740 | 75/351 (21%) | |||
ArfGap | 406..519 | CDD:279720 | 34/132 (26%) | ||
Prevents interaction with ITGB1 when S-554 is not phosphorylated. /evidence=ECO:0000250 | 525..566 | 2/40 (5%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 525..562 | 2/36 (6%) | |||
Ank_2 | 575..670 | CDD:289560 | 24/100 (24%) | ||
ANK repeat | 575..602 | CDD:293786 | 5/31 (16%) | ||
ANK | <592..692 | CDD:238125 | 24/100 (24%) | ||
ANK repeat | 606..637 | CDD:293786 | 7/30 (23%) | ||
ANK repeat | 639..670 | CDD:293786 | 10/31 (32%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5347 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |