DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ArfGAP3 and terfa

DIOPT Version :9

Sequence 1:	NP_001097664.2	Gene:	ArfGAP3 / 40487	FlyBaseID:	FBgn0037182	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	XP_009299378.1	Gene:	terfa / 192316	ZFINID:	ZDB-GENE-020419-38	Length:	610	Species:	Danio rerio

Alignment Length:	402	Identity:	83/402 - (20%)
Similarity:	125/402 - (31%)	Gaps:	119/402 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PSKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTF-VRSTNL 71
            |||          |..|.:.:..|..|:             |:  |||.|. |:...| :.|...
Zfish   225 PSK----------RTPPHSSAAEDHGAE-------------CV--SAVSRQ-GLQQVFDLLSEQY 263

  Fly    72 DTNWTWLQL--------RQMQLGGNANAAQFFRAHNCSTTDAQVKYNS---------RAAQLYRD 119
            ....::.||        :|.|.||.|......   ..|.|..|....|         |.|.:...
Zfish   264 GVGISFFQLQDSVEVEAQQQQEGGVAGPELCL---TLSETPMQTVILSDTEEQDEPRRYAGMTIS 325

  Fly   120 KLCAQAQQAMKTHGTKLHLEQTDKSEGNEAAREEDF-FAQCDNEVD------------------F 165
            :|..:....:....|  |:|..::.|.....|..|: ....|.|.|                  .
Zfish   326 RLVQEEDSQISAEHT--HIEDDEEEEQTHTHRGGDWVVVLSDLESDDLDVQAGPVSSPSLRHTPK 388

  Fly   166 NVQNNNVSKQDP--------NPPTVAPVISVETQQGGAPSVNLLNSVVPAAVPSSIGARKVQPKK 222
            |.||.:.|..:|        .|..:....:...||..:.|   .:|....:.|    ||...|..
Zfish   389 NRQNQHSSLSEPQCSSTQRSTPARLCKRSNTRVQQSESES---QSSPAHCSTP----ARPSHPSN 446

  Fly   223 GGLGARKVGGLGATKVKTNFADIEARANAANEMKTSAAAAPVVKPQTAEDELETVASMRLAYQEL 287
            .....||       |..:....||: :::.||..|.|||....:.|..:.....|:|    ..|.
Zfish   447 PRSSTRK-------KTPSRRRIIES-SDSENEQTTPAAATHTPRGQRQQHRSIRVSS----GSEP 499

  Fly   288 SMQKTREEAKLKTMDPA--------KAKQMERLGMGFNLRGSD-MAHSALGDMETIQQSAAPKAK 343
            .:..|...|..:...|.        ::|.::..|:..|....| :.|:          |.||..|
Zfish   500 EVDSTSPAAHTRRSTPTSTHTRTTKRSKWLDASGIQDNWSDEDSLFHT----------STAPAKK 554

  Fly   344 L-----SLLESE 350
            .     |:.|||
Zfish   555 YTRKMWSVQESE 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	25/121 (21%)
terfa	XP_009299378.1	TRFH	7..203	CDD:238174
		SANT_TRF	558..606	CDD:212558	4/9 (44%)
		SANT	560..606	CDD:197842	4/7 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	1	0.960