Protein Alignment ArfGAP3 and Agfg1

DIOPT Version :9

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_006496493.1
• Gene: Agfg1 / 15463
• MGIID: 1333754
• Length: 577
• Species: Mus musculus
• Alignment Length: 625
• Identity: 133/625 - (21%)
• Similarity: 211/625 - (33%)
• Gaps: 171/625 - (27%)

  Fly     5 AAGPSKQEIESVFSRLR---AQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLG-VHLTF 65
            ||...:::.|.....||   ..|.|:.||||..:.||:.::|.|.|:|..||...|.|. .|.
Mouse     2 AASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLNPPHR-- 64

  Fly    66 VRSTNLDTNWTWLQLRQMQLGGN--------------ANAAQFFRAHNCSTTDAQVKYNSR---- 112
            |:|.:: |.:|..::..:|..||              ::|...||.........|.||..:
Mouse    65 VKSISM-TTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEKYEKKRWYV 128

  Fly   113 -------AAQLYRDKLCAQAQQAMKTHGTK------------LHLEQ--------TDKSEGNEAA 150
                   .|.::.....:.|.....|...|            |||.:        ..:|:|.:..
Mouse   129 PPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGESAPALHLNKGTPSQSPVVGRSQGQQQE 193

  Fly   151 REE---------DFFA-------QCDNEVDFNVQNNNVSKQDPNPPTVAPVISVETQQGGAPSVN 199
            :::         |.||       ...|..:|...|::.::...|    |...:.:.....:.|.|
Mouse   194 KKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSAN----ADFANFDAFGQSSGSSN 254

  Fly   200 LLNSVVPAAVPSSIGARKVQPKKGGLGARKVGGLGATKVKTNFADIEARANAANEMKTSAAAAPV 264
            .  ...|.|..||.     ||:..|      |..|:  |..|||..:      |..|:|:|....
Mouse   255 F--GGFPTASHSSF-----QPQTTG------GSAGS--VNANFAHFD------NFPKSSSADFGT 298

  Fly   265 VKPQTAEDELETVASMRLAYQELSMQKTREEAKLKTMDPA-KAKQMERLGMGFNLRG-------- 320
            .....:.....||:  :::..:..:|...:.|.|..:|.. .|.|....|.||...|
Mouse   299 FSTSQSHQTASTVS--KVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVV 361

  Fly   321 --------SDMAHSALGDMETIQQSAAPKAKLSLLESENFFTDFSLYGNSSSGGGG----GGSSE 373
                    |...::||.:::::..|||        .|.|.:|..|   |:||...|    |.|::
Mouse   362 SVPSHSSASSDKYAALAELDSVFSSAA--------TSSNAYTPTS---NASSSVFGTVPVGASAQ 415

  Fly   374 KRESSVG--------------------GTSKLDKFELDALGYETIEPIGGSHSNI---------- 408
            .:.:|.|                    ..|..:.|:.:|.|...:.  |..||.:
Mouse   416 TQPASSGPAPFGATPSTNPFVAATGPSAASSTNPFQTNARGATGLS--GAMHSQVFPHAHFAATF 478

  Fly   409 -TSMFSRSNDYDKPKTSAPVKKNSGSSQTHTKGGTSTDPVI-AQQKFGNSKGFGSDQYFASEQSS 471
             |:..|....:..|...:.....|||.|         .|.. ||..|.....|......|...:.
Mouse   479 GTASMSMPAGFGTPAQYSLPTSFSGSFQ---------QPAFPAQAAFPQQTAFSQQPNGAGFATF 534

  Fly   472 ADVSASLNRF-QGSRAISSSDYFGDGSPGGTGGNRASSVN 510
            ......:..| |.:.|..||:.|..|:|.|.....:||.|
Mouse   535 GQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQLPTGSSSTN 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	33/132 (25%)
Agfg1	XP_006496493.1	COG5347	8..268	CDD:227651	56/273 (21%)
		ArfGap_AGFG1	13..128	CDD:350082	32/117 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900