Protein Alignment ArfGAP3 and Asap1

DIOPT Version :9

• Sequence 1: NP_001097664.2
• Gene: ArfGAP3 / 40487
• FlyBaseID: FBgn0037182
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_006520455.1
• Gene: Asap1 / 13196
• MGIID: 1342335
• Length: 1223
• Species: Mus musculus
• Alignment Length: 560
• Identity: 123/560 - (21%)
• Similarity: 189/560 - (33%)
• Gaps: 192/560 - (34%)

  Fly     9 SKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTNLDT 73
            :|..||.| .||   |.|..|.||.:..|||.|...||..||:||.:||.:|||::.::|..||.
Mouse   529 TKAIIEDV-QRL---PGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELDK 589

  Fly    74 NWTWLQLRQMQLGGN-------AN---------------------AAQF----FRAHNCSTTDAQ 106
            ..|...|....:|.|       ||                     .|::    |....|:::.|:
Mouse   590 LGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAKYVDHRFSRKTCASSSAK 654

  Fly   107 VKYNSRAAQLYRDKLC-----AQAQQAM--------KTHGTKLHLEQTDKSEGNEAAREEDFFAQ 158
            :.....|.: .||.|.     |:..:.|        :...|.|||          |.|..|..:.
Mouse   655 LNELLEAIK-SRDLLALIQVYAEGVELMEPLLEPGQELGETALHL----------AVRTADQTSL 708

  Fly   159 CDNEVDFNVQN-NNVSKQDPNPPTVAPVIS-------VETQQGGAPSVNLLNSVVPAAVPSSIGA 215
              :.|||.||| .|:.||.....||....|       ::......|:|:::|.....|:
Mouse   709 --HLVDFLVQNCGNLDKQTSVGNTVLHYCSMYGKPECLKLLLRSKPTVDIVNQNGETAL------ 765

  Fly   216 RKVQPKKGGLGARKVGGLGATKVKTNFADIEARANAANEMKTSAAAAPVVKPQTAEDELETVAS- 279
                                        ||..|                :|....||.|....|
Mouse   766 ----------------------------DIAKR----------------LKATQCEDLLSQAKSG 786

  Fly   280 -----MRLAYQELSMQKTREEAKLKTMDPAKAKQMERLGMGFNLRGSDMAHSALGDMETIQQSAA 339
                 :.:.|:....|...:|:.....|.....:.||     :.|.....||:         |.:
Mouse   787 KFNPHVHVEYEWNLRQDEMDESDDDLDDKPSPIKKER-----SPRPQSFCHSS---------SIS 837

  Fly   340 PKAKLSL----------LESENFFTDFSLYGNSSSGGGGGGSSE-----KRESSVGGTSKLDKFE 389
            |:.||:|          ..|...||: .::.::|:......:||     .|.:..|.|
Mouse   838 PQDKLALPGFSTPRDKQRLSYGAFTN-QIFASTSTDLPTSPTSEAPPLPPRNAGKGPT------- 894

  Fly   390 LDALGYETIEPIGGSHSNITSMFSRSNDYDKPKTSAPVKKNSGSSQTHTKGGTSTDPVIAQQKFG 454
                |..:..|:|...|:.:|..|:.    :|....|..|.           |.:||........
Mouse   895 ----GPPSTLPLGTQTSSGSSTLSKK----RPPPPPPGHKR-----------TLSDPPSPLPHGP 940

  Fly   455 NSKG---FGSDQYFASEQSSADVSASLNRFQG-SRAISSS 490
            .:||   :|:|....|...:|      |:|:| |:..|:|
Mouse   941 PNKGAIPWGNDVGPLSSSKTA------NKFEGLSQQASTS 974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	38/135 (28%)
Asap1	XP_006520455.1	BAR_ASAP1	138..344	CDD:153325
		PH_ASAP	407..513	CDD:270071
		ArfGap_ASAP1	528..649	CDD:350073	37/123 (30%)
		ANK repeat	692..725	CDD:293786	15/44 (34%)
		Ank_2	696..>768	CDD:372319	23/117 (20%)
		ANK repeat	727..758	CDD:293786	5/30 (17%)
		Atrophin-1	845..>1109	CDD:367360	33/163 (20%)
		SH3_ASAP1	1165..1221	CDD:212898

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900