DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ArfGAP3 and adap2

DIOPT Version :9

Sequence 1:	NP_001097664.2	Gene:	ArfGAP3 / 40487	FlyBaseID:	FBgn0037182	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	XP_021329475.1	Gene:	adap2 / 100331455	ZFINID:	ZDB-GENE-070912-21	Length:	418	Species:	Danio rerio

Alignment Length:	175	Identity:	43/175 - (24%)
Similarity:	70/175 - (40%)	Gaps:	36/175 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SKQEIESVFSRLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTNLDT 73
            ::::.:.:...|...|.|..|.||.|..|.|:|...|||:|:.||..||||.. ::.::|..||.
Zfish     3 NREKNKKILLELVKLPENNCCADCGAADPDWASCKLGIFVCLTCSGTHRNLPT-ISRIKSIRLDF 66

  Fly    74 NWTWLQLRQMQLGGNANAAQFF-----------RAHNCSTTDAQ---VKYNSR-----------A 113
             |....::.|:..||.:|..|:           ..|:|.....|   .||...           .
Zfish    67 -WDDELVQFMKANGNCSAKNFYEKCVPVFYYRPHPHDCEVLREQWIRAKYERMEFTEEKTERPYT 130

  Fly   114 AQLYRDKLCAQAQQ---------AMKTHGTKLHLEQTDKSEGNEA 149
            |.:|...|..:.:.         .:..|...|...:.|:|:|.:|
Zfish   131 ADVYEGMLWKKGRDNGQFLERKFVLSVHDFTLKYYKEDESKGPKA 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	36/128 (28%)
adap2	XP_021329475.1	ArfGap	8..123	CDD:307528	34/116 (29%)
		PH1_ADAP	134..240	CDD:270072	8/42 (19%)
		PH2_ADAP	254..361	CDD:241282
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910