DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ArfGAP3 and LOC100005008

DIOPT Version :9

Sequence 1:	NP_001097664.2	Gene:	ArfGAP3 / 40487	FlyBaseID:	FBgn0037182	Length:	553	Species:	Drosophila melanogaster
Sequence 2:	XP_001344168.4	Gene:	LOC100005008 / 100005008	-ID:	-	Length:	958	Species:	Danio rerio

Alignment Length:	191	Identity:	51/191 - (26%)
Similarity:	73/191 - (38%)	Gaps:	49/191 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 RLRAQPANKSCFDCAAKAPTWSSVTYGIFICIDCSAVHRNLGVHLTFVRSTNLDTN-WTWLQLRQ 82
            ||.:.|.||.|.||.|..|.|:||...:.||..|:..||::|...:.||...||.. ||...::.
Zfish   391 RLWSSPCNKVCADCGAANPEWASVNLLVVICEACAGAHRSMGSSRSKVRGLKLDDKVWTEPLIQL 455

  Fly    83 MQLGGNANAAQFFRAHNCSTTDAQV---------------KYNS---RAA-----------QLYR 118
            ..|.||..|...: .||...|: |:               ||:.   |.|           |..|
Zfish   456 FVLHGNKTANNVW-GHNIPPTE-QISPLASPDQRAEFILAKYHKGLYRKAHPLAASQKLLDQRLR 518

  Fly   119 DKLCAQAQQ---AMKTHGTKLHLEQTD----------KSEG----NEAAREEDFFAQCDNE 162
            :.:|..|.:   ::...|.|:....:|          :|.|    .|..|..:|....|.|
Zfish   519 EVVCGPAVEETVSLLCSGAKVSCSSSDPELKSAIAVAESAGQALQTELLRHNEFVEAPDFE 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ArfGAP3	NP_001097664.2	ArfGap	17..121	CDD:214518	39/131 (30%)
LOC100005008	XP_001344168.4	PH-like	291..375	CDD:302622
		PH	292..380	CDD:278594
		ArfGap	386..503	CDD:279720	36/113 (32%)
		RhoGAP	769..939	CDD:295372
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900