DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment POTEG and Actc1

DIOPT Version :9

Sequence 1:	NP_001005356.1	Gene:	POTEG / 404785	HGNCID:	33896	Length:	508	Species:	Homo sapiens
Sequence 2:	NP_062056.1	Gene:	Actc1 / 29275	RGDID:	2026	Length:	377	Species:	Rattus norvegicus

Alignment Length:	172	Identity:	36/172 - (20%)
Similarity:	62/172 - (36%)	Gaps:	31/172 - (18%)

- Green bases have known domain annotations that are detailed below.

Human   226 LEHGTDPNIPDEYGNTALHYAIYNEDKLMAK--ALLLYGADIESK-NKHGLTPLLLGVHEQKQQV 287
            :|||...|..|.  ....|:..|||.::..:  ..||..|.:..| |:..:|.::..........
  Rat    73 IEHGIITNWDDM--EKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMY 135

Human   288 VKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLL-------LEQNIDVSSQDLSG------- 338
            |  .|:...:|.|..|  .|.::|....|....|.:.       ....:|::.:||:.
  Rat   136 V--AIQAVLSLYASGR--TTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILT 196

Human   339 -------QTAREYAVSSHHNVICQLLSDYKEKQMLKVSSENS 373
                   .||....|......:|.:..|: |.:|...:|.:|
  Rat   197 ERGYSFVTTAEREIVRDIKEKLCYVALDF-ENEMATAASSSS 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
POTEG	NP_001005356.1	Ank_4	143..193	CDD:290365
		ANK	167..292	CDD:238125	16/68 (24%)
		ANK 1	172..201
		ANK repeat	174..203	CDD:293786
		Ank_2	177..269	CDD:289560	13/45 (29%)
		ANK repeat	205..236	CDD:293786	4/9 (44%)
		ANK 2	205..234		3/7 (43%)
		ANK	233..357	CDD:238125	28/147 (19%)
		ANK repeat	238..269	CDD:293786	8/33 (24%)
		ANK 3	238..267		7/30 (23%)
		Ank_2	243..335	CDD:289560	20/101 (20%)
		ANK repeat	271..302	CDD:293786	5/30 (17%)
		ANK 4	271..300		4/28 (14%)
		ANK repeat	304..335	CDD:293786	5/37 (14%)
		ANK 5	304..333		5/35 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	367..488		2/7 (29%)
Actc1	NP_062056.1	PTZ00281	4..377	CDD:173506	36/172 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
HGNC	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100127
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710