DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trxr-2 and TRR2

DIOPT Version :9

Sequence 1:	NP_524216.1	Gene:	Trxr-2 / 40475	FlyBaseID:	FBgn0037170	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_011974.1	Gene:	TRR2 / 856506	SGDID:	S000001148	Length:	342	Species:	Saccharomyces cerevisiae

Alignment Length:	237	Identity:	58/237 - (24%)
Similarity:	100/237 - (42%)	Gaps:	54/237 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 VTRVDLRDKKVEYVNSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPRYPDIPGAV---E 197
            |::|||..|         .||........|.|      ||::.:::|.|...:...:||..   :
Yeast   110 VSKVDLSSK---------PFRLWTEFNEDAEP------VTTDAIILATGASAKRMHLPGEETYWQ 159

  Fly   198 LGITSDDIFS-----YEREPGRTLVVGAGYVGLECACFLKGLGYEPTVMVRSIVLRGFDRQMSEL 257
            .||::..:..     :..:|  ..|:|.|....|.|.||.....:..::||.      |...:.:
Yeast   160 QGISACAVCDGAVPIFRNKP--LAVIGGGDSACEEAEFLTKYASKVYILVRK------DHFRASV 216

  Fly   258 LAAMMTER--GIPFLGTTIPKAVERQADGRLL--VRYRNTTTQMDGSDVFDTVLWAIGR------ 312
            :.....|:  .|..|..|:  |:|.:.||:||  :|.:||.:.::.....:.:.:|||.
Yeast   217 IMQRRIEKNPNIIVLFNTV--ALEAKGDGKLLNMLRIKNTKSNVENDLEVNGLFYAIGHSPATDI 279

  Fly   313 -KGLIEDLNLDAAG-VKTHDDKIVVDAAEATSVPHIFAVGDI 352
             ||.:::   :..| :||      |..:..||||..||.||:
Yeast   280 VKGQVDE---EETGYIKT------VPGSSLTSVPGFFAAGDV 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trxr-2	NP_524216.1	NADB_Rossmann	29..>68	CDD:304358
		TGR	31..515	CDD:273624	58/237 (24%)
		NADB_Rossmann	<144..239	CDD:304358	21/102 (21%)
		Pyr_redox	214..288	CDD:278498	20/77 (26%)
		Pyr_redox_dim	388..497	CDD:280934
TRR2	NP_011974.1	TRX_reduct	28..338	CDD:273540	58/237 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345484
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840