Protein Alignment Trxr2 and IRC15

DIOPT Version :10

• Sequence 1: NP_524216.1
• Gene: Trxr2 / 40475
• FlyBaseID: FBgn0037170
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_015308.1
• Gene: IRC15 / 856090
• SGDID: S000005938
• Length: 499
• Species: Saccharomyces cerevisiae
• Alignment Length: 515
• Identity: 121/515 - (23%)
• Similarity: 213/515 - (41%)
• Gaps: 77/515 - (14%)

  Fly    33 YDLVVLGGGSAGLACAKEAAGCGARVLCFDYVKPTPVGTKWGIGGTCVNVGCIPKK--------- 88
            ||::|:|.|..|...|.:|:..|....|.|        .:..:||..:..|.:|.|
Yeast    18 YDVLVIGCGPGGFTAAMQASQAGLLTACVD--------QRASLGGAYLVDGAVPSKTLLYESYLY 74

  Fly    89 -LMHQASLLGEAVHEAVAYGWNVDDTNIRP---DWRKLVRSVQNHIKSVNWVTRVDLRDKKVEYV 149
             |:.|..|:.:.            .|.:.|   |.:....:::::|:.:..|.:.:|....|...
Yeast    75 RLLQQQELIEQR------------GTRLFPAKFDMQAAQSALKHNIEELGNVYKRELSKNNVTVY 127

  Fly   150 NSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPRYPDIPGAV---ELGITSDDIFSYERE 211
            ...|.|:|.|.:| :|..|.:...|.::|:|||.|.  .....||..   :..|:||...|.:..
Yeast   128 KGTAAFKDPHHVE-IAQRGMKPFIVEAKYIVVATGS--AVIQCPGVAIDNDKIISSDKALSLDYI 189

  Fly   212 PGRTLVVGAGYVGLECACFLKGLGYEPTVM-VRSIVLRGFDRQMSELLAAMMTERGIPFLGTTIP 275
            |.|..::|.|.:|||.||....||...|:: .:|.:.:..|.:::.....::..:||.||..|..
Yeast   190 PSRFTIMGGGTIGLEIACIFNNLGSRVTIVESQSEICQNMDNELASATKTLLQCQGIAFLLDTRV 254

  Fly   276 KAVERQADGRLLVRYRNTTTQMDGSDVFDTVLWAIGRKGLIEDLNLDAAGVKTHD--DKIVVDAA 338
            :..|..|.|:|.:...|..::.......|.::.:|||:.|::.|::.:.|:...|  :.:.|...
Yeast   255 QLAEADAAGQLNITLLNKVSKKTYVHHCDVLMVSIGRRPLLKGLDISSIGLDERDFVENVDVQTQ 319

  Fly   339 EATSVPHIFAVGDIIYGRPELTPVAILSGRLLARRLF-----AGSTQLMDYADVATTVFTPLEYS 398
            .....|||..:||:..|     |:..|.....|.|..     .||....:.......::...:..
Yeast   320 SLLKYPHIKPIGDVTLG-----PMLALKAEEQAIRAIQSIGCTGSDGTSNCGFPPNVLYCQPQIG 379

  Fly   399 CVGMSEETAIELRGADNIEVFHGYYKPTEFFIPQKSVRH-------------CYLKAVAEVSGDQ 450
            .||.:||...:.|        ..|.|....|  .::||:             .::|.:.: |.|.
Yeast   380 WVGYTEEGLAKAR--------IPYQKGRVLF--SQNVRYNTLLPREENTTVSPFIKVLID-SRDM 433

  Fly   451 KILGLHYIGPVAGEVIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFTR-LSITKRSGRDP 509
            ||||:|.|...|.|::...:.|:..|||...:......||:.:|.|.: :.:...:|..|
Yeast   434 KILGVHMINDDANELLSQASMAVSLGLTAHDVCKVPFPHPSLSESFKQAVQLAMANGTSP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr2	NP_524216.1	TGR	31..515	CDD:273624	121/515 (23%)
IRC15	NP_015308.1	Lpd	18..487	CDD:440861	119/507 (23%)