DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trxr-2 and TRR1

DIOPT Version :9

Sequence 1:	NP_524216.1	Gene:	Trxr-2 / 40475	FlyBaseID:	FBgn0037170	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_010640.1	Gene:	TRR1 / 851955	SGDID:	S000002761	Length:	319	Species:	Saccharomyces cerevisiae

Alignment Length:	304	Identity:	71/304 - (23%)
Similarity:	118/304 - (38%)	Gaps:	74/304 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 GEAVHEAVAYGWNVDDTNIRP--------------DWRKLVRSVQNHIKSVNWVTRVDLRDKKVE 147
            |.|.|.|..|   :....|:|              ........::|.....:.:|..:|.|:..|
Yeast    12 GPAAHTAAIY---LARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGSELMDRMRE 73

  Fly   148 YVNSMATFRDSHTIEYVAMP----------GAEHRQVTSEYVVVAVGGRPRYPDIPGAV---ELG 199
            ......|...:.|:..|.:.          ..:...||::.:::|.|...:...:||..   :.|
Yeast    74 QSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKG 138

  Fly   200 ITSDDIFS-----YEREPGRTLVVGAGYVGLECACFLKGLGYEPTVMVRSIVLRGFDRQMSELLA 259
            |::..:..     :..:|  ..|:|.|....|.|.||...|.:..::||...||.         :
Yeast   139 ISACAVCDGAVPIFRNKP--LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA---------S 192

  Fly   260 AMMTERG-----IPFLGTTIPKAVERQADGRLL--VRYRNT----TTQMDGSDVFDTVLWAIGR- 312
            .:|.:|.     |..|..|:  |:|.:.||:||  :|.:||    .|.:..|.:|    :|||.
Yeast   193 TIMQKRAEKNEKIEILYNTV--ALEAKGDGKLLNALRIKNTKKNEETDLPVSGLF----YAIGHT 251

  Fly   313 ---KGLIEDLNLDAAG-VKTHDDKIVVDAAEATSVPHIFAVGDI 352
               |.:...::.|.|| :||      |..:..||||..||.||:
Yeast   252 PATKIVAGQVDTDEAGYIKT------VPGSSLTSVPGFFAAGDV 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trxr-2	NP_524216.1	NADB_Rossmann	29..>68	CDD:304358
		TGR	31..515	CDD:273624	71/304 (23%)
		NADB_Rossmann	<144..239	CDD:304358	21/112 (19%)
		Pyr_redox	214..288	CDD:278498	23/80 (29%)
		Pyr_redox_dim	388..497	CDD:280934
TRR1	NP_010640.1	TRX_reduct	5..315	CDD:273540	71/304 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345486
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840