Protein Alignment Trxr2 and Txnrd2

DIOPT Version :10

• Sequence 1: NP_524216.1
• Gene: Trxr2 / 40475
• FlyBaseID: FBgn0037170
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_072106.1
• Gene: Txnrd2 / 50551
• RGDID: 61960
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 263/520 - (50%)
• Similarity: 353/520 - (67%)
• Gaps: 21/520 - (4%)

  Fly    14 ALRSSLGWCR----------------LAASRPRYDYDLVVLGGGSAGLACAKEAAGCGARVLCFD 62
            |||.|.|..|                .:|:..:.::||:|:||||.|||||||||..|.:|...|
  Rat     7 ALRGSSGRFRPQTRVLTRGTRGAAGAASAAGGQQNFDLLVIGGGSGGLACAKEAAQLGRKVAVAD 71

  Fly    63 YVKPTPVGTKWGIGGTCVNVGCIPKKLMHQASLLGEAVHEAVAYGWNVDDTNIRPDWRKLVRSVQ 127
            ||:|:|.|||||:||||||||||||||||||:|||..:.:|..|||.|... ::.:|:.:..:||
  Rat    72 YVEPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAQHYGWEVAQP-VQHNWKAMAEAVQ 135

  Fly   128 NHIKSVNWVTRVDLRDKKVEYVNSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPRYP-D 191
            ||:||:||..||.|:|:||:|.|..|:|.:.||:..|...| :..|::::::|:|.||||:|| .
  Rat   136 NHVKSLNWGHRVQLQDRKVKYFNIKASFVNEHTVHGVDKAG-KVTQLSAKHIVIATGGRPKYPTQ 199

  Fly   192 IPGAVELGITSDDIFSYEREPGRTLVVGAGYVGLECACFLKGLGYEPTVMVRSIVLRGFDRQMSE 256
            :.||:|.||||||||..:..||:||||||.||.||||.||.|:|.:.|||:||:.|||||:||:.
  Rat   200 VKGALEHGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSVPLRGFDQQMAS 264

  Fly   257 LLAAMMTERGIPFLGTTIPKAVERQADGRLLVRYRNTTTQMDGSDVFDTVLWAIGRKGLIEDLNL 321
            |:...|...|..||...:|..:.:....:|.|.:.:..:..:....||||||||||.....:|||
  Rat   265 LVTEHMESHGTRFLKGCVPSLIRKLPTNQLQVTWEDLASGKEDVGTFDTVLWAIGRVPETRNLNL 329

  Fly   322 DAAGVKTH--DDKIVVDAAEATSVPHIFAVGDIIYGRPELTPVAILSGRLLARRLFAGSTQLMDY 384
            :.|||.|:  :.||:|||.||||||||:|:||:..|||||||.||.:|:|||:|||..|:.||:|
  Rat   330 EKAGVNTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMNY 394

  Fly   385 ADVATTVFTPLEYSCVGMSEETAIELRGADNIEVFHGYYKPTEFFIPQKSVRHCYLKAVAEVSGD 449
            ::|.|||||||||.|||:|||.|:.|.|.::|||:|.||||.||.:..:....||:|.|......
  Rat   395 SNVPTTVFTPLEYGCVGLSEEEAVALHGQEHIEVYHAYYKPLEFTVADRDASQCYIKMVCMREPP 459

  Fly   450 QKILGLHYIGPVAGEVIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFTRLSITKRSGRDPTPASC 514
            |.:||||::||.||||.||||..::.|.:...::.|||||||.:||..:|.|:||||.|||...|
  Rat   460 QLVLGLHFLGPNAGEVTQGFALGIQCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLDPTVTGC 524

  Fly   515  514
              Rat   525  524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trxr2	NP_524216.1	TGR	31..515	CDD:273624	256/487 (53%)
Txnrd2	NP_072106.1	TGR	41..526	CDD:273624	256/486 (53%)