DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11425 and PLPP1

DIOPT Version :9

Sequence 1:NP_649395.1 Gene:CG11425 / 40472 FlyBaseID:FBgn0037167 Length:305 Species:Drosophila melanogaster
Sequence 2:NP_795714.1 Gene:PLPP1 / 8611 HGNCID:9228 Length:285 Species:Homo sapiens


Alignment Length:262 Identity:98/262 - (37%)
Similarity:148/262 - (56%) Gaps:30/262 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 FNLSLRPPIRLLVDLVLLGLLIVLVENFRRLWGPPTKRGFFCDDESLMYPYHENTVSPTLLHWLG 67
            |:.:..|.:.|.|..|||..:.:.|....:::  |.:|||||.|.|:.||||::||:.|:|..:|
Human     2 FDKTRLPYVALDVLCVLLASMPMAVLKLGQIY--PFQRGFFCKDNSINYPYHDSTVTSTVLILVG 64

  Fly    68 LYLPLISLVVLESF-----LSHRKDMAPWPTLWPVYNTVRWFLYGYVSNDLLKGIGKQALGRLRP 127
            :.||:.|:::.|:.     |.|.........:..:|..:..||:|..::..|..|.|.::|||||
Human    65 VGLPISSIILGETLSVYCNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRP 129

  Fly   128 HFFAVCSPHFPDGS--SCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYG 190
            ||..||.   ||.|  :|.|    |.::|   |.||.|     .|.:::..:||.||||:.:.|.
Human   130 HFLDVCD---PDWSKINCSD----GYIEY---YICRGN-----AERVKEGRLSFYSGHSSFSMYC 179

  Fly   191 LVFVALHLRRRRWPLRGS---LLSPVLQLACVALAWFVAISRVIDYKHHWSDVAAGSLLGAGSAL 252
            ::||||:|:.|   ::|.   ||.|.||...||::.:|.:|||.|||||||||..|.:.||..|:
Human   180 MLFVALYLQAR---MKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAI 241

  Fly   253 AV 254
            .|
Human   242 LV 243

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11425NP_649395.1 PAP2_wunen 96..255 CDD:239479 67/164 (41%)
PLPP1NP_795714.1 PAP2_wunen 99..244 CDD:239479 67/163 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165144639
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0671
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S2766
OMA 1 1.010 - - QHG48083
OrthoDB 1 1.010 - - D1354951at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10165
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
65.900

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