Protein Alignment CG11425 and PLPPR3

DIOPT Version :10

• Sequence 1: NP_649395.1
• Gene: CG11425 / 40472
• FlyBaseID: FBgn0037167
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_079164.1
• Gene: PLPPR3 / 79948
• HGNCID: 23497
• Length: 746
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 73/309 - (23%)
• Similarity: 112/309 - (36%)
• Gaps: 92/309 - (29%)

  Fly    10 PIRLLVDLVLLGLLIV------LVENFRRLWGPPTKRGFFCDDESLMYPY---HENTVSPTLLHW 65
            |....|:|.::...||      |.:.|:     |.|.||.|.|.:|..||   :|..:...:|..
Human    19 PCFYFVELPIVASSIVSLYFLELTDLFK-----PAKVGFQCYDRTLSMPYVETNEELIPLLMLLS 78

  Fly    66 LGLYLPLISLVVLESFLSHRKDMAPWPTLWP----------------------VYNTVRW---FL 105
            |....|..|::|.|..|...:.     .||.                      :..|||:   .:
Human    79 LAFAAPAASIMVAEGMLYCLQS-----RLWGRAGGPAGAEGSINAGGCNFNSFLRRTVRFVGVHV 138

  Fly   106 YGYVSNDLLKGIGKQALGRLRPHFFAVCSPHFP-DGSSCLDESHRGALKYHTDYECRPNLSQ--- 166
            :|..:..|:..:.:.|.|...|.|..||.|::. .|:||               |..|.::|
Human   139 FGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSC---------------EVNPYITQDIC 188

  Fly   167 --ATEEMIRDVNVSFPSGHSAMAFYGLVFV-----------ALHLRRRRWPLRGS---------- 208
              .....|.....:|||.|:.::.:..|:|           ||.|.|....|..:
Human   189 SGHDIHAILSARKTFPSQHATLSAFAAVYVSVSPAPHCPSQALLLTRGEPSLTPTPMPQMYFNSV 253

  Fly   209 ------LLSPVLQLACVALAWFVAISRVIDYKHHWSDVAAGSLLGAGSA 251
                  ||.|:|..|....|....::::..|:.|..||.||.|:|||.|
Human   254 ISDTTKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIA 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11425	NP_649395.1	PAP2_wunen	96..255	CDD:239479	47/214 (22%)
PLPPR3	NP_079164.1	PAP2_wunen	129..306	CDD:239479	47/189 (25%)