DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11425 and plpp3

DIOPT Version :9

Sequence 1:	NP_649395.1	Gene:	CG11425 / 40472	FlyBaseID:	FBgn0037167	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	XP_001919561.1	Gene:	plpp3 / 557680	ZFINID:	ZDB-GENE-060526-241	Length:	312	Species:	Danio rerio

Alignment Length:	240	Identity:	79/240 - (32%)
Similarity:	131/240 - (54%)	Gaps:	28/240 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LVLLGLLIVLVENFRRLWGPPTKRGFFCDDESLMYPY-HENTVSPTLLHWLGLYLPLISLVVLES 80
            |.:|..||:.....:     |..|||:|.|:|:.||| :.:|:|..:|...|:.:.:.|:|:.|.
Zfish    45 LAVLPFLIIETSTIK-----PYHRGFYCSDQSIQYPYKNGDTISDAVLCAAGILIVIFSIVIGEC 104

  Fly    81 FLSH-----RKDMAPWPTLWPVYNTVRWFLYGYVSNDLLKGIGKQALGRLRPHFFAVCSPHFPDG 140
            :..|     .|.....|.:..:|..|..|::|...:.....|.|.::||:||||..||.|::
Zfish   105 YRIHYLSQGSKSFVGNPYVSALYRQVGVFIFGCAVSQSFTDIAKVSVGRMRPHFLDVCRPNY--- 166

  Fly   141 SSCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYGLVFVALHLRRR-RWP 204
             |.:|.|    |.|.|:|.|..:.|:     :::...||.|||::.:.|.::::|.:|:.| .|
Zfish   167 -STIDCS----LGYITEYTCTGDPSK-----VQEARKSFFSGHASFSMYTMLYLAFYLQSRFTW- 220

  Fly   205 LRGS-LLSPVLQLACVALAWFVAISRVIDYKHHWSDVAAGSLLGA 248
             ||: ||.|:||...:.:|::..:|||.|:|||.:||.||.:.||
Zfish   221 -RGARLLRPLLQFTLLMMAFYTGLSRVSDHKHHPTDVLAGFVQGA 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11425	NP_649395.1	PAP2_wunen	96..255	CDD:239479	55/155 (35%)
plpp3	XP_001919561.1	PAP2_wunen	125..271	CDD:239479	55/155 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577771
Domainoid	1	1.000	47	1.000	Domainoid score	I11977
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10165
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950