DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11425 and Plpp2

DIOPT Version :9

Sequence 1:	NP_649395.1	Gene:	CG11425 / 40472	FlyBaseID:	FBgn0037167	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_056632.2	Gene:	Plpp2 / 50784	MGIID:	1354945	Length:	276	Species:	Mus musculus

Alignment Length:	252	Identity:	84/252 - (33%)
Similarity:	125/252 - (49%)	Gaps:	32/252 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VLLGLLIVLVEN----FRRLWGPPTKRGFFCDDESLMYPYHENTVSPTLLHWLGLYLPLISLVVL 78
            |||.:|.|||.:    ...|...|.||||:|.|:|:.|||..:|::..|:..:.:...:|.:.:.
Mouse     8 VLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSIRYPYRPDTITHGLMAGVIITATVILVSLG 72

  Fly    79 ESFLSH------RKDMAPWPTLWPVYNTVRWFLYGYVSNDLLKGIGKQALGRLRPHFFAVCSPHF 137
            |::|.:      |.:...:  :..:|..:..||:|...:..|..:.|..:|||||.|.|||.|
Mouse    73 EAYLVYTDRLYSRSNFNNY--VAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVCDP-- 133

  Fly   138 PDGSSCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYGLVFVALHLRRR- 201
                   |.|......|.....||.:.:..||     ..:||.||||:...|.::|:||:::.|
Mouse   134 -------DWSQVNCSGYVQLEVCRGSPANVTE-----ARLSFYSGHSSFGMYCMLFLALYVQARL 186

  Fly   202 --RWPLRGSLLSPVLQLACVALAWFVAISRVIDYKHHWSDVAAGSLLGAGSALAVTR 256
              :|   ..||.|.:|...||.|.:|..:||.|:|||||||..|.|.||..|....|
Mouse   187 CWKW---ARLLRPTVQFFLVAFAIYVGYTRVSDHKHHWSDVLVGLLQGALVACLTVR 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11425	NP_649395.1	PAP2_wunen	96..255	CDD:239479	58/161 (36%)
Plpp2	NP_056632.2	PAP2_wunen	94..239	CDD:239479	58/161 (36%)
		Phosphatase sequence motif I. /evidence=ECO:0000250\|UniProtKB:O34349	117..125		4/7 (57%)
		Phosphatase sequence motif II. /evidence=ECO:0000250\|UniProtKB:O34349	164..167		1/2 (50%)
		Phosphatase sequence motif III. /evidence=ECO:0000250\|UniProtKB:O34349	212..223		7/10 (70%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	251..276
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834795
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10165
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950