DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11425 and Plpp4

DIOPT Version :9

Sequence 1:	NP_649395.1	Gene:	CG11425 / 40472	FlyBaseID:	FBgn0037167	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001074432.1	Gene:	Plpp4 / 381925	MGIID:	2685936	Length:	271	Species:	Mus musculus

Alignment Length:	265	Identity:	67/265 - (25%)
Similarity:	106/265 - (40%)	Gaps:	84/265 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IRLLVDLVLLGLLIV--LVENFRRLWGPPTKRGFFCDDESLMY--PYHENTVSPT-LLHWLGLYL 70
            |.:.|..:|.|:.:.  .::.|:|:..|         :|..:|  |..::...|| |:..:....
Mouse     6 IEIGVRALLFGVFVFTEFLDPFQRVIQP---------EEIWLYKNPLVQSDNIPTRLMFAISFLT 61

  Fly    71 PLISLVVL------------ESFLSHRKDMAPWPTLWPVYNTVRWFLYGYVSNDLLKGIGKQALG 123
            ||..:.|:            |:||:....:|               |.|..:|.:     |..:|
Mouse    62 PLAVICVVKIIRRTDKTEIKEAFLAVSLALA---------------LNGVCTNTI-----KLIVG 106

  Fly   124 RLRPHFFAVCSPHFPDGSSCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAF 188
            |.||.||..|   ||||            ..:::..|     ....:::.:...||||.||:.||
Mouse   107 RPRPDFFYRC---FPDG------------VMNSEMRC-----TGDPDLVSEGRKSFPSIHSSFAF 151

  Fly   189 YGLVFVALHL-----------RRRRWPLRGSLLSPVLQLACVALAWFVAISRVIDYKHHWSDVAA 242
            .||.|...:|           |.:.|    .|.:.:|.|.|   |..:|:||:.||||||.|...
Mouse   152 SGLGFTTFYLAGKLHCFTESGRGKSW----RLCAAILPLYC---AMMIALSRMCDYKHHWQDSFV 209

  Fly   243 GSLLG 247
            |.::|
Mouse   210 GGVIG 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11425	NP_649395.1	PAP2_wunen	96..255	CDD:239479	47/163 (29%)
Plpp4	NP_001074432.1	PAP2_containing_1_like	37..225	CDD:239484	59/225 (26%)
		Phosphatase sequence motif I. /evidence=ECO:0000250\|UniProtKB:Q5VZY2	102..110		3/7 (43%)
		Phosphatase sequence motif II. /evidence=ECO:0000250\|UniProtKB:Q5VZY2	143..146		2/2 (100%)
		Phosphatase sequence motif III. /evidence=ECO:0000250\|UniProtKB:Q5VZY2	195..205		7/9 (78%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834781
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001532
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X622
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830