DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11425 and Plpp2

DIOPT Version :9

Sequence 1:	NP_649395.1	Gene:	CG11425 / 40472	FlyBaseID:	FBgn0037167	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_640345.1	Gene:	Plpp2 / 246115	RGDID:	628893	Length:	276	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	93/280 - (33%)
Similarity:	136/280 - (48%)	Gaps:	45/280 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VLLGLLIVLVEN----FRRLWGPPTKRGFFCDDESLMYPYHENTVSPTLLHWLGLYLPLISLVVL 78
            |||.:|.|||.:    ...|...|.||||:|.|:|:.|||..:|::    |.|...:.:.:.|||
  Rat     8 VLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSIRYPYRPDTIT----HGLMAGVIITATVVL 68

  Fly    79 ----ESFLSH------RKDMAPWPTLWPVYNTVRWFLYGYVSNDLLKGIGKQALGRLRPHFFAVC 133
                |::|.:      |.|...:  :..:|..:..||:|...:..|..:.|..:|||||.|.|||
  Rat    69 VSSGEAYLVYTDRLYSRSDFNNY--VAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVC 131

  Fly   134 SPHFPDGSSCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYGLVFVALHL 198
            .|         |.|......|.....||.:.:..||     ..:||.||||:...|.::|:||::
  Rat   132 DP---------DWSRVNCSGYVQVEVCRGSPANVTE-----ARLSFYSGHSSFGMYCMLFLALYV 182

  Fly   199 RRR---RWPLRGSLLSPVLQLACVALAWFVAISRVIDYKHHWSDVAAGSLLGAGSALAVTRAAAS 260
            :.|   :|   ..||.|.:|...||.|.:|..:||.|.|||||||..|.|.||..| .:|....|
  Rat   183 QARLCWKW---ARLLRPTVQFFLVAFAIYVGYTRVSDNKHHWSDVLVGLLQGALVA-CLTVCYVS 243

  Fly   261 EELQWR----CQDSLASAKQ 276
            :..:.|    ||::..|.::
  Rat   244 DFFKSRPPQSCQENEESERK 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11425	NP_649395.1	PAP2_wunen	96..255	CDD:239479	58/161 (36%)
Plpp2	NP_640345.1	PAP2_wunen	94..239	CDD:239479	58/162 (36%)
		Phosphatase sequence motif I. /evidence=ECO:0000250\|UniProtKB:O34349	117..125		4/7 (57%)
		Phosphatase sequence motif II. /evidence=ECO:0000250\|UniProtKB:O34349	164..167		1/2 (50%)
		Phosphatase sequence motif III. /evidence=ECO:0000250\|UniProtKB:O34349	212..223		7/10 (70%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	252..276		3/12 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338377
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10165
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950