Protein Alignment CG11425 and SGPP2

DIOPT Version :9

• Sequence 1: NP_649395.1
• Gene: CG11425 / 40472
• FlyBaseID: FBgn0037167
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_689599.2
• Gene: SGPP2 / 130367
• HGNCID: 19953
• Length: 399
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 47/217 - (21%)
• Similarity: 70/217 - (32%)
• Gaps: 87/217 - (40%)

  Fly    64 HWLGLYLPLISLVVLESFLSHRKDMAPWPTLWPVYNTVRWFL---YGYVSNDLLKGIGKQALGRL 125
            ||           .::.:||.|.             .:.|.|   .|.|:.|:||
Human   110 HW-----------NIDPYLSRRL-------------IIIWVLVMYIGQVAKDVLK---------- 140

  Fly   126 RPHFFAVCSPHFPDGSSCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYG 190
                       :|..||                   |.:.:..:.:|.:..:  ||.| |||...
Human   141 -----------WPRPSS-------------------PPVVKLEKRLIAEYGM--PSTH-AMAATA 172

  Fly   191 LVFVAL--HLRRRRWPLRGSLLSPVLQLA-CVALAWFVAISRVIDYKHHWSDVAAGSLLGAGSAL 252
            :.|..|  .:.|.::|.       ||.|. .|..:..|.:||:....|...||..|.|:.| ..:
Human   173 IAFTLLISTMDRYQYPF-------VLGLVMAVVFSTLVCLSRLYTGMHTVLDVLGGVLITA-LLI 229

  Fly   253 AVTRAAASEELQWRCQDSLASA 274
            .:|..|      |...|.|.||
Human   230 VLTYPA------WTFIDCLDSA 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11425	NP_649395.1	PAP2_wunen	96..255	CDD:239479	35/164 (21%)
SGPP2	NP_689599.2	PAP2_SPPase1	84..233	CDD:239482	40/197 (20%)
		Phosphatase sequence motif I. /evidence=ECO:0000305	136..144		4/28 (14%)
		Phosphatase sequence motif II. /evidence=ECO:0000305	163..166		2/2 (100%)
		Phosphatase sequence motif III. /evidence=ECO:0000305	206..217		3/10 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900