Protein Alignment CG11426 and PLPP1

DIOPT Version :10

• Sequence 1: NP_649394.1
• Gene: CG11426 / 40471
• FlyBaseID: FBgn0037166
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_795714.1
• Gene: PLPP1 / 8611
• HGNCID: 9228
• Length: 285
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 114/311 - (36%)
• Similarity: 171/311 - (54%)
• Gaps: 42/311 - (13%)

  Fly    31 DRRMTQRLLVELLVVVVLVIPICVYEFA-VDPVRRGFFCDDESISYPFQDNTITPVMLGLIVGL- 93
            |:.....:.:::|.|::..:|:.|.:.. :.|.:|||||.|.||:||:.|:|:|..:| ::||:
Human     3 DKTRLPYVALDVLCVLLASMPMAVLKLGQIYPFQRGFFCKDNSINYPYHDSTVTSTVL-ILVGVG 66

  Fly    94 LPALVMVVVEYVSHLRAGD-ISATVDLLGWR-------VSTWYVELGRQSTYFCFGLLLTFDATE 150
            ||         :|.:..|: :|...:||...       ::|.|..:|.    |.||...:...|:
Human    67 LP---------ISSIILGETLSVYCNLLHSNSFIRNNYIATIYKAIGT----FLFGAAASQSLTD 118

  Fly   151 VGKYTIGRLRPHFLAVCQPQIADGSM--CSDPVNLHRYMENYDCAGEGFTVEDVRQARLSFPSGH 213
            :.||:|||||||||.||.|   |.|.  |||     .|:|.|.|.|   ..|.|::.||||.|||
Human   119 IAKYSIGRLRPHFLDVCDP---DWSKINCSD-----GYIEYYICRG---NAERVKEGRLSFYSGH 172

  Fly   214 SSLAFYAMIYVALYLQRKITWRGSKLSRHFVQFAVVMVAWYTALSRVMDHWHHWSDVLSGSLLGV 278
            ||.:.|.|::||||||.::....::|.|..:||.:|.|:.|..||||.|:.|||||||:|.:.|.
Human   173 SSFSMYCMLFVALYLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGA 237

  Fly   279 AGALITAHYIARMFDDGASNILSGGLRRENTAATLQEEVCPTTPPPYSVNN 329
            ..|::.|.|::..|.:..|   ....:.|::..||.|  .|||...|..|:
Human   238 LVAILVAVYVSDFFKERTS---FKERKEEDSHTTLHE--TPTTGNHYPSNH 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11426	NP_649394.1	PAP2_wunen	130..285	CDD:239479	70/156 (45%)
PLPP1	NP_795714.1	PAP2_wunen	99..244	CDD:239479	71/159 (45%)