DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11426 and SGPP1

DIOPT Version :10

Sequence 1:NP_649394.1 Gene:CG11426 / 40471 FlyBaseID:FBgn0037166 Length:340 Species:Drosophila melanogaster
Sequence 2:NP_110418.1 Gene:SGPP1 / 81537 HGNCID:17720 Length:441 Species:Homo sapiens


Alignment Length:155 Identity:33/155 - (21%)
Similarity:58/155 - (37%) Gaps:39/155 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 PASASGSAAGSTGPSSDRR---MTQRLLV--ELLVVVVLVIPI-CVYEFAVDPVRRGFFCDDESI 73
            |.......|...||:|.||   :.:..|.  |..:..|...|: |::.|..:.....|:.    :
Human    86 PNGVRNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSNWPLYCLFCFGTELGNELFYI----L 146

  Fly    74 SYPFQDNTITPVMLGLIVGLLPALVMVVVEYVSHLRAGDISATVDLLGW---------RVSTWY- 128
            .:||....:.|     :||....::.|:|.|:.       ..|.|::.|         ::..:| 
Human   147 FFPFWIWNLDP-----LVGRRLVVIWVLVMYLG-------QCTKDIIRWPRPASPPVVKLEVFYN 199

  Fly   129 VELGRQSTYFCFG-------LLLTF 146
            .|....||:...|       :|||:
Human   200 SEYSMPSTHAMSGTAIPISMVLLTY 224

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11426NP_649394.1 PAP2_wunen 130..285 CDD:239479 7/24 (29%)
SGPP1NP_110418.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 25..110 7/23 (30%)
PAP2_SPPase1 126..275 CDD:239482 23/115 (20%)
Phosphatase sequence motif I. /evidence=ECO:0000305 178..186 2/7 (29%)
Phosphatase sequence motif II. /evidence=ECO:0000305 205..208 1/2 (50%)
Phosphatase sequence motif III. /evidence=ECO:0000305 248..259
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.