DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11426 and Plppr4

DIOPT Version :9

Sequence 1:	NP_649394.1	Gene:	CG11426 / 40471	FlyBaseID:	FBgn0037166	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001001508.2	Gene:	Plppr4 / 295401	RGDID:	727806	Length:	766	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	72/265 - (27%)
Similarity:	122/265 - (46%)	Gaps:	19/265 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 VELLVVVVLVIPICVYEF--AVDPVRRGFFCDDESISYPFQDNTITPVMLGLIVGLL---PALVM 99
            |||.::...|:.:...|.  ...||..||.|.|.|:|.|:.:.|...:...:::.|.   ||:.:
  Rat    74 VELPILASSVVSLYFLELTDVFKPVHSGFSCYDRSLSMPYIEPTQEAIPFLMLLSLAFAGPAITI 138

  Fly   100 VVVEYV-----SHLRAG-DISATVDLLGWRVSTWYVELGRQSTYFCFGLLLTFDATEVGKYTIGR 158
            :|.|.:     |..|.| .:...::..|...:::.....|......|||..|...|::.:.:.|.
  Rat   139 MVGEGILYCCLSKRRNGAGLEPNINAGGCNFNSFLRRAVRFVGVHVFGLCSTALITDIIQLSTGY 203

  Fly   159 LRPHFLAVCQPQIADGSM-CSDPVNLHRYMENYDCAGEGFTVEDVRQARLSFPSGHSSLAFYAMI 222
            ..|:||.||:|.....:: |.:    :.|:....|:|...||  :...|.||||.|::||.:|.:
  Rat   204 QAPYFLTVCKPNYTSLNVSCKE----NSYIVEDICSGSDLTV--INSGRKSFPSQHATLAAFAAV 262

  Fly   223 YVALYLQRKITWRGSKLSRHFVQFAVVMVAWYTALSRVMDHWHHWSDVLSGSLLGVAGALITAHY 287
            ||::|....:| ..|||.:..:.|..::......|:|:..:.:|..||..|.|:|...||....|
  Rat   263 YVSMYFNSTLT-DSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLY 326

  Fly   288 IARMF 292
            ....|
  Rat   327 AVGNF 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11426	NP_649394.1	PAP2_wunen	130..285	CDD:239479	46/155 (30%)
Plppr4	NP_001001508.2	PAP2_wunen	175..324	CDD:239479	46/155 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	454..503
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	510..529
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	634..654
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	672..705
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	741..766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338337
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.830