DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11426 and Plpp2

DIOPT Version :9

Sequence 1:	NP_649394.1	Gene:	CG11426 / 40471	FlyBaseID:	FBgn0037166	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_640345.1	Gene:	Plpp2 / 246115	RGDID:	628893	Length:	276	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	99/257 - (38%)
Similarity:	147/257 - (57%)	Gaps:	20/257 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LLVELLVVVVLVIPICVYEFAVDPVRRGFFCDDESISYPFQDNTITPVMLGLIVG-LLPALVMVV 101
            :|:::|.|:|..:|..:......|.:|||:|.|:||.||::.:|||.   ||:.| ::.|.|::|
  Rat     8 VLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSIRYPYRPDTITH---GLMAGVIITATVVLV 69

  Fly   102 VEYVSHLRAGD-ISATVDLLGWRVSTWYVELGRQSTYFCFGLLLTFDATEVGKYTIGRLRPHFLA 165
            ....::|...| :.:..|...: |:..|..||.    |.||..::...|::.||.||||||.|||
  Rat    70 SSGEAYLVYTDRLYSRSDFNNY-VAAIYKVLGT----FLFGAAVSQSLTDLAKYMIGRLRPSFLA 129

  Fly   166 VCQPQIADGSMCSDPVNLHRYMENYDCAGEGFTVEDVRQARLSFPSGHSSLAFYAMIYVALYLQR 230
            ||.|   |.|.    ||...|::...|.|   :..:|.:|||||.|||||...|.|:::|||:|.
  Rat   130 VCDP---DWSR----VNCSGYVQVEVCRG---SPANVTEARLSFYSGHSSFGMYCMLFLALYVQA 184

  Fly   231 KITWRGSKLSRHFVQFAVVMVAWYTALSRVMDHWHHWSDVLSGSLLGVAGALITAHYIARMF 292
            ::.|:.::|.|..|||.:|..|.|...:||.|:.|||||||.|.|.|...|.:|..|::..|
  Rat   185 RLCWKWARLLRPTVQFFLVAFAIYVGYTRVSDNKHHWSDVLVGLLQGALVACLTVCYVSDFF 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11426	NP_649394.1	PAP2_wunen	130..285	CDD:239479	67/154 (44%)
Plpp2	NP_640345.1	PAP2_wunen	94..239	CDD:239479	68/158 (43%)
		Phosphatase sequence motif I. /evidence=ECO:0000250\|UniProtKB:O34349	117..125		6/7 (86%)
		Phosphatase sequence motif II. /evidence=ECO:0000250\|UniProtKB:O34349	164..167		1/2 (50%)
		Phosphatase sequence motif III. /evidence=ECO:0000250\|UniProtKB:O34349	212..223		6/10 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	252..276
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338373
Domainoid	1	1.000	159	1.000	Domainoid score	I3984
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3693
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		mtm9041
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10165
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X571
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.960