DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11426 and Plppr3

DIOPT Version :9

Sequence 1:	NP_649394.1	Gene:	CG11426 / 40471	FlyBaseID:	FBgn0037166	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_859009.2	Gene:	Plppr3 / 216152	MGIID:	2388640	Length:	716	Species:	Mus musculus

Alignment Length:	327	Identity:	82/327 - (25%)
Similarity:	133/327 - (40%)	Gaps:	58/327 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 VELLVVVVLVIPICVYEFA--VDPVRRGFFCDDESISYPF---QDNTITPVMLGLIVGLLPALVM 99
            |||.:|...::.:...|..  ..|.:.||.|.|.::|.|:   .:..|..:||..:....||..:
Mouse    24 VELPIVASSIVSLYFLELTDLFKPAKVGFQCYDRALSMPYVETNEELIPLLMLLSLAFAAPAASI 88

  Fly   100 VVVE---YVSHLR-----AGDISATVDLLGWRVSTWYVELGRQSTYFCFGLLLTFDATEVGKYTI 156
            :|.|   |....|     .|.:..:::..|...:::.....|......|||..|...|:|.:...
Mouse    89 MVGEGMVYCLQSRLWGRGPGGVEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLAT 153

  Fly   157 GRLRPHFLAVCQPQIA-DGSMC-SDPVNLHRYMENYDCAGEGFTVEDVRQARLSFPSGHSSLAFY 219
            |...|.||.||:|... .|:.| |:|     |:....|:|.  ....:..||.:|||.|::|:.:
Mouse   154 GYHTPFFLTVCKPNYTLLGTSCESNP-----YITQDICSGH--DTHAILSARKTFPSQHATLSAF 211

  Fly   220 AMIYVALYLQRKITWRGSKLSRHFVQFAVVMVAWYTALSRVMDHWHHWSDVLSGSLLGVA-GALI 283
            |.:||::|....|: ..:||.:..:.||..:.|....|:::..:..|..||.:|.|:|.. .|.:
Mouse   212 AAVYVSMYFNAVIS-DTTKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYL 275

  Fly   284 TAHYIARMFDDGASNILSGGLRRENTAATLQEEVCPTTPPP---------------YSVNNSFSE 333
            ..|.:.                  |..|...|:| ||..|.               |..|.|.|.
Mouse   276 ACHAVG------------------NFQAPPAEKV-PTPAPAKDALRALTQRGHESMYQQNKSVST 321

  Fly   334 DQ 335
            |:
Mouse   322 DE 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11426	NP_649394.1	PAP2_wunen	130..285	CDD:239479	46/157 (29%)
Plppr3	NP_859009.2	PAP2_wunen	127..276	CDD:239479	46/156 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	311..335		5/13 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	416..515
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	548..589
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	630..651
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	663..693
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834784
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830