DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11426 and Plpp1

DIOPT Version :9

Sequence 1:	NP_649394.1	Gene:	CG11426 / 40471	FlyBaseID:	FBgn0037166	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_032273.1	Gene:	Plpp1 / 19012	MGIID:	108412	Length:	284	Species:	Mus musculus

Alignment Length:	307	Identity:	109/307 - (35%)
Similarity:	162/307 - (52%)	Gaps:	35/307 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 DRRMTQRLLVELLVVVVLVIPICVYEFA-VDPVRRGFFCDDESISYPFQDNTITPVMLGLIVGL- 93
            |:.....:.::::.|::..:|:.:.:.. |.|.:|||||.|.|:.||:.|:|| |..:..|:||
Mouse     3 DKTRLPYVALDVICVLLAAMPMTILKLGKVYPFQRGFFCTDNSVKYPYHDSTI-PSRILAILGLG 66

  Fly    94 LPALVMVVVE----YVSHLRAGDISATVDLLGWRVSTWYVELGRQSTYFCFGLLLTFDATEVGKY 154
            ||...|.:.|    |.:.|.:.......     .::|.|..:|.    |.||:..:...|::.||
Mouse    67 LPIFSMSIGESLSVYFNVLHSNSFVGNP-----YIATIYKAVGA----FLFGVSASQSLTDIAKY 122

  Fly   155 TIGRLRPHFLAVCQPQIADGSM--CSDPVNLHRYMENYDCAGEGFTVEDVRQARLSFPSGHSSLA 217
            |||.|||||||:|.|   |.|.  |||     .|:|:|.|.|   ..|.|::.||||.|||||.:
Mouse   123 TIGSLRPHFLAICNP---DWSKINCSD-----GYIEDYICQG---NEEKVKEGRLSFYSGHSSFS 176

  Fly   218 FYAMIYVALYLQRKITWRGSKLSRHFVQFAVVMVAWYTALSRVMDHWHHWSDVLSGSLLGVAGAL 282
            .|.|::||||||.::....::|.|..:||.::..:.|..||||.|:.||||||..|.:.|.|.|:
Mouse   177 MYCMLFVALYLQARMKGDWARLLRPMLQFGLIAFSIYVGLSRVSDYKHHWSDVTVGLIQGAAMAI 241

  Fly   283 ITAHYIARMFDDGASNILSGGLRRENTAATLQEEVCPTTPPPYSVNN 329
            :.|.|::..|.|..|   ....:.|:...||.|......   ||.|:
Mouse   242 LVALYVSDFFKDTHS---YKERKEEDPHTTLHETASSRN---YSTNH 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11426	NP_649394.1	PAP2_wunen	130..285	CDD:239479	68/156 (44%)
Plpp1	NP_032273.1	PAP2_wunen	99..244	CDD:239479	69/159 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834747
Domainoid	1	1.000	159	1.000	Domainoid score	I4068
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I3731
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	1	1.000	-	-		mtm8794
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	O	PTHR10165
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X571
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.860