Protein Alignment CG11437 and PLPP5

DIOPT Version :10

• Sequence 1: NP_649393.1
• Gene: CG11437 / 40470
• FlyBaseID: FBgn0037165
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: XP_024303075.2
• Gene: PLPP5 / 84513
• HGNCID: 25026
• Length: 293
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 66/291 - (22%)
• Similarity: 96/291 - (32%)
• Gaps: 96/291 - (32%)

  Fly    19 ILLGIYGAALVVLPQQLSTAQRGFHCSDTSLKYPYRQPWL------------------------- 58
            :.|.::.|.||.  :.|...||.....:..|   ||.|::
Human    16 VRLALFAAFLVT--ELLPPFQRLIQPEEMWL---YRNPYVEAEYFPTKPMFVRGERSSFLPPHDP 75

  Fly    59 -TKVHL------TIAVVAL--PAAFVLVVEMLRAAVVPSSTELTQRFVFVGVRIPRFISECYKAI 114
             ::.||      |..|:|.  |.:.:.:.:.|:.|....|.:                 .|..|
Human    76 ASRGHLCVFHPETAFVIAFLSPLSLIFLAKFLKKADTRDSRQ-----------------ACLAA- 122

  Fly   115 GVYLFGLGLTLAAI--RLTKHSTGRLRPYFFDICQPTWGTEGGESCSDVTAQNSTLYLEDFSCTE 177
                 .|.|.|..:  ...|...||.||.||..|.|    :|             |...|..||
Human   123 -----SLALALNGVFTNTIKLIVGRPRPDFFYRCFP----DG-------------LAHSDLMCT- 164

  Fly   178 FAASQDLLALVRHSFPSGFVSTTCYAMGFLIFYSQARL--FAP------WLRLVRASLQLACCSL 234
              ..:|::...|.|||||..|.....:.|..||...:|  |.|      |    |....|:....
Human   165 --GDKDVVNEGRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPQGRGKSW----RFCAFLSPLLF 223

  Fly   235 ALVVCWERISTYQNHLTDVAAGAALGGWMAF 265
            |.|:...|...|::|..||..|:.:|...|:
Human   224 AAVIALSRTCDYKHHWQDVLVGSMIGMTFAY 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11437	NP_649393.1	PAP2_wunen	109..268	CDD:239479	46/167 (28%)
PLPP5	XP_024303075.2	PAP2_containing_1_like	43..260	CDD:239484	59/262 (23%)