back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11438 and PLPP3

DIOPT Version :10

Sequence 1:	NP_649392.1	Gene:	CG11438 / 40469	FlyBaseID:	FBgn0037164	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_003704.3	Gene:	PLPP3 / 8613	HGNCID:	9229	Length:	311	Species:	Homo sapiens

Alignment Length:	261	Identity:	98/261 - (37%)
Similarity:	147/261 - (56%)	Gaps:	27/261 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 RPFRRGFFCGDETLSYPARDG-TISSKVIIAIVLGVPNAVIVVVELFRQLPGGPLREAGGKRDSC 95
            :|:.|||:|.||::.||.:.| ||:..|:.|:.:.:....|:..|.:|      :......|.:.
Human    60 KPYHRGFYCNDESIKYPLKTGETINDAVLCAVGIVIAILAIITGEFYR------IYYLKKSRSTI 118

  Fly    96 RIAHRLGVLYRQVIFYLYGLAMVTFTTMLTKLCLGRLRPHFLAVCQPMLPDGS--SCQDAQNLGR 158
            :..: :..||:||..:|:|.|:....|.:.|:.:||||||||:||.   ||.|  :|.:.
Human   119 QNPY-VAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCN---PDFSQINCSEG----- 174

  Fly   159 YIDSFTCSNANMTDYQFKELYQSFPSGHASMAMYAMLYLAIYLQAALSTRVSKLLKHLLQFLFVM 223
            ||.::.|..   .|.:.:|..:||.|||||.:||.||||.:||||..:.|.::||:.||||..:|
Human   175 YIQNYRCRG---DDSKVQEARKSFFSGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFTLIM 236

  Fly   224 FGWYVSLTRIIDYYHHWSDVLAGAALGVVFAWLTSAYVADLFAGKRWPKTGYS--ANTLRKPQVS 286
            ..:|..|:|:.|:.||.||||||.|.|.:.|.....:|:|||.    .||..|  |..:||..:|
Human   237 MAFYTGLSRVSDHKHHPSDVLAGFAQGALVACCIVFFVSDLFK----TKTTLSLPAPAIRKEILS 297

  Fly   287 P 287
            |
Human   298 P 298

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.