Protein Alignment laza and PLPP5

DIOPT Version :10

• Sequence 1: NP_649391.1
• Gene: laza / 40468
• FlyBaseID: FBgn0037163
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: XP_024303075.2
• Gene: PLPP5 / 84513
• HGNCID: 25026
• Length: 293
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 61/215 - (28%)
• Similarity: 93/215 - (43%)
• Gaps: 42/215 - (19%)

  Fly     6 RGFFCSDLSIRYPYKDCTITVPMLLLMMLLLPMLFVAVVEIMRICKRFRTRLYFRNLWRAEATFS 70
            ||..|    :.:|      ....::..:..|.::|:|         :|..:...|:..:|....|
Human    78 RGHLC----VFHP------ETAFVIAFLSPLSLIFLA---------KFLKKADTRDSRQACLAAS 123

  Fly    71 FGFIATYLTTELAKHAVGRLRPHFFHGCQPRLDDGSSCSDLQNAELYVEQFHCTNNNLSTRQIRE 135
            .......:.|...|..|||.||.||:.|.|   ||.:.|||.          ||.:.   ..:.|
Human   124 LALALNGVFTNTIKLIVGRPRPDFFYRCFP---DGLAHSDLM----------CTGDK---DVVNE 172

  Fly   136 LHVSFPSAHSSLSFYSMVLLALYVHG-----VWRGRGGVRVLRHVLQFLLLMAALCVSLSRVADY 195
            ...||||.|||.:|..:...:.|:.|     ..:|||  :..|.......|:.|..::|||..||
Human   173 GRKSFPSGHSSFAFAGLAFASFYLAGKLHCFTPQGRG--KSWRFCAFLSPLLFAAVIALSRTCDY 235

  Fly   196 WHHWSDVLAGALLGVTYAAI 215
            .|||.|||.|:::|:|:|.:
Human   236 KHHWQDVLVGSMIGMTFAYV 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
laza	NP_649391.1	PAP2_wunen	62..217	CDD:239479	52/159 (33%)
PLPP5	XP_024303075.2	PAP2_containing_1_like	43..260	CDD:239484	61/215 (28%)