Protein Alignment laza and PLPPR3

DIOPT Version :9

• Sequence 1: NP_649391.1
• Gene: laza / 40468
• FlyBaseID: FBgn0037163
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_079164.1
• Gene: PLPPR3 / 79948
• HGNCID: 23497
• Length: 746
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 107/493 - (21%)
• Similarity: 168/493 - (34%)
• Gaps: 181/493 - (36%)

  Fly     5 KRGFFCSDLSIRYPYKDCT-ITVPMLLLMMLLL--PMLFVAVVEIMRICKRFRTRLY-------- 58
            |.||.|.|.::..||.:.. ..:|:|:|:.|..  |...:.|.|.|..|  .::||:
Human    49 KVGFQCYDRTLSMPYVETNEELIPLLMLLSLAFAAPAASIMVAEGMLYC--LQSRLWGRAGGPAG 111

  Fly    59 -----------FRNLWRAEATF----SFGFIATYLTTELAKHAVGRLRPHFFHGCQPRLD-DGSS 107
                       |.:..|....|    .||..||.|.|::.:.|.|...|.|...|:|... .|:|
Human   112 AEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTS 176

  Fly   108 CSDLQNAELYVEQFHCTNNN----LSTRQIRELHVSFPSAHSSLSFYSMVLLA------------ 156
            |    ....|:.|..|:.::    ||.|:      :|||.|::||.::.|.::
Human   177 C----EVNPYITQDICSGHDIHAILSARK------TFPSQHATLSAFAAVYVSVSPAPHCPSQAL 231

  Fly   157 ----------------LYVHGVWRGRGGVRVLRHVLQFLLLMAALCVSLSRVADYWHHWSDVLAG 205
                            :|.:.|....  .::|:.:|.|...:||....|:::..|..|..||.||
Human   232 LLTRGEPSLTPTPMPQMYFNSVISDT--TKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAG 294

  Fly   206 ALLGVTYAAITAAY-VGNL-----------------LRRQTS-------------STGRIPP--- 236
            .|:|...||..|.: |||.                 ||..|.             ||..:.|
Human   295 FLIGAGIAAYLACHAVGNFQAPPAEKPAAPAPAKDALRALTQRGHDSVYQQNKSVSTDELGPPGR 359

  Fly   237 ---------------------SLNYSHHLHHQLMADNNNSTASAKVHFLAAAASAS--------M 272
                                 |::.........||..|..|.|   |.|..|::.|        |
Human   360 LEGAPRPVAREKTSLGSLKRASVDVDLLAPRSPMAKENMVTFS---HTLPRASAPSLDDPARRHM 421

  Fly   273 TTTTPLDDIQDSDV-----EDSRDCRD-------------------SEDSHDSQDSHAENEDDNE 313
            |...|||..:...:     :.|.:.|.                   :|:..:.:|...|.|::.|
Human   422 TIHVPLDASRSKQLISEWKQKSLEGRGLGLPDDASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEE 486

  Fly   314 E--------VYKSQMSRP------VTP----PTDLTHV 333
            |        :|.:..:||      :.|    |..|.|:
Human   487 EDEGPAPPSLYPTVQARPGLGPRVILPPRAGPPPLVHI 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
laza	NP_649391.1	PAP2_wunen	62..217	CDD:239479	48/191 (25%)
PLPPR3	NP_079164.1	PAP2_wunen	129..306	CDD:239479	47/188 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144673
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1621899at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750