DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment laza and plpp1a

DIOPT Version :9

Sequence 1:	NP_649391.1	Gene:	laza / 40468	FlyBaseID:	FBgn0037163	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	XP_697507.5	Gene:	plpp1a / 569053	ZFINID:	ZDB-GENE-080225-26	Length:	282	Species:	Danio rerio

Alignment Length:	235	Identity:	85/235 - (36%)
Similarity:	128/235 - (54%)	Gaps:	26/235 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FKRGFFCSDLSIRYPYKDCTITVPMLLLMMLLLPMLFVAVVEIMRI-CKRFRTRL----YFRNLW 63
            ::|||||:|.|||||:...|:|..:|..:...||:..:.:.|.:.: ..|.::..    |...::
Zfish    35 YQRGFFCNDESIRYPFHSSTVTSTVLYTVGFTLPICSMIIGECLSVYLNRIKSNSFCNGYVACVY 99

  Fly    64 RAEATFSFGFIATYLTTELAKHAVGRLRPHFFHGCQPRLDDGS--SCSDLQNAELYVEQFHCTNN 126
            :|..||.||...:...|::||:::|||||||...|:|   |.|  :|:    |..|:|.|.||..
Zfish   100 KAIGTFVFGAAISQSLTDIAKYSIGRLRPHFLDVCKP---DWSKINCT----AGAYIEDFVCTGK 157

  Fly   127 NLSTRQIRELHVSFPSAHSSLSFYSMVLLALY----VHGVWRGRGGVRVLRHVLQFLLLMAALCV 187
            .   ..:.|..:||.|.|||.|.|.|:.||||    :...|     .|:||..|||.|:.|::..
Zfish   158 E---SVVNEGRLSFYSGHSSFSMYCMLFLALYLQARMQAEW-----ARLLRPTLQFFLIAASVYT 214

  Fly   188 SLSRVADYWHHWSDVLAGALLGVTYAAITAAYVGNLLRRQ 227
            .||||:||.|||||||.|.:.|...|.:...:|.:..:::
Zfish   215 GLSRVSDYKHHWSDVLTGLIQGAIVALLVVFFVSDFFKKK 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
laza	NP_649391.1	PAP2_wunen	62..217	CDD:239479	65/160 (41%)
plpp1a	XP_697507.5	PAP2_wunen	98..244	CDD:239479	65/160 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577776
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.820