Protein Alignment laza and Plpp4

DIOPT Version :10

• Sequence 1: NP_649391.1
• Gene: laza / 40468
• FlyBaseID: FBgn0037163
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_001074432.1
• Gene: Plpp4 / 381925
• MGIID: 2685936
• Length: 271
• Species: Mus musculus
• Alignment Length: 256
• Identity: 71/256 - (27%)
• Similarity: 104/256 - (40%)
• Gaps: 69/256 - (26%)

  Fly    19 YKDCTI---TVPMLLLMML--LLPMLFVAVVEIMRICKRFRTRLYFRNLWRAEAT-FSFGFIATY 77
            ||:..:   .:|..|:..:  |.|:..:.||:|:|               |.:.| ....|:|..
Mouse    39 YKNPLVQSDNIPTRLMFAISFLTPLAVICVVKIIR---------------RTDKTEIKEAFLAVS 88

  Fly    78 LT-------TELAKHAVGRLRPHFFHGCQPRLDDGSSCSDLQNAELYVEQFHCTNNNLSTRQIRE 135
            |.       |...|..|||.||.||:.|.|   ||     :.|:|:     .||.:   ...:.|
Mouse    89 LALALNGVCTNTIKLIVGRPRPDFFYRCFP---DG-----VMNSEM-----RCTGD---PDLVSE 137

  Fly   136 LHVSFPSAHSSLSFYSMVLLALYVHG-----VWRGRGGVRVLRHVLQFLLLMAALCVSLSRVADY 195
            ...||||.|||.:|..:.....|:.|     ...|||  :..|.....|.|..|:.::|||:.||
Mouse   138 GRKSFPSIHSSFAFSGLGFTTFYLAGKLHCFTESGRG--KSWRLCAAILPLYCAMMIALSRMCDY 200

  Fly   196 WHHWSDVLAGALLGVTYAAI-----------TAAY-------VGNLLRRQTSSTGRIPPSL 238
            .|||.|...|.::|:.:|.|           ||.:       |...|:::...|....|||
Mouse   201 KHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPTSLKKEERPTADSAPSL 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
laza	NP_649391.1	PAP2_wunen	62..217	CDD:239479	53/178 (30%)
Plpp4	NP_001074432.1	PAP2_containing_1_like	37..225	CDD:239484	63/218 (29%)
		Phosphatase sequence motif I. /evidence=ECO:0000250|UniProtKB:Q5VZY2	102..110		4/7 (57%)
		Phosphatase sequence motif II. /evidence=ECO:0000250|UniProtKB:Q5VZY2	143..146		2/2 (100%)
		Phosphatase sequence motif III. /evidence=ECO:0000250|UniProtKB:Q5VZY2	195..205		6/9 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..271		4/13 (31%)