DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment laza and Plpp1

DIOPT Version :9

Sequence 1:	NP_649391.1	Gene:	laza / 40468	FlyBaseID:	FBgn0037163	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_032273.1	Gene:	Plpp1 / 19012	MGIID:	108412	Length:	284	Species:	Mus musculus

Alignment Length:	264	Identity:	93/264 - (35%)
Similarity:	139/264 - (52%)	Gaps:	23/264 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHTFKRGFFCSDLSIRYPYKDCTITVPMLLLMMLLLPMLFVAVVEIMRI------CKRFRTRLYF 59
            ::.|:|||||:|.|::|||.|.||...:|.::.|.||:..:::.|.:.:      ...|....|.
Mouse    32 VYPFQRGFFCTDNSVKYPYHDSTIPSRILAILGLGLPIFSMSIGESLSVYFNVLHSNSFVGNPYI 96

  Fly    60 RNLWRAEATFSFGFIATYLTTELAKHAVGRLRPHFFHGCQPRLDDGS--SCSDLQNAELYVEQFH 122
            ..:::|...|.||..|:...|::||:.:|.|||||...|.|   |.|  :|||     .|:|.:.
Mouse    97 ATIYKAVGAFLFGVSASQSLTDIAKYTIGSLRPHFLAICNP---DWSKINCSD-----GYIEDYI 153

  Fly   123 CTNNNLSTRQIRELHVSFPSAHSSLSFYSMVLLALYVHGVWRGRGGVRVLRHVLQFLLLMAALCV 187
            |..|.   .:::|..:||.|.|||.|.|.|:.:|||:....:| ...|:||.:|||.|:..::.|
Mouse   154 CQGNE---EKVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKG-DWARLLRPMLQFGLIAFSIYV 214

  Fly   188 SLSRVADYWHHWSDVLAGALLGVTYAAITAAYVGNLLRRQTSSTGRIPPSLNYSHHLHHQLMADN 252
            .||||:||.||||||..|.:.|...|.:.|.||.:..:...|...|....   .|...|:..:..
Mouse   215 GLSRVSDYKHHWSDVTVGLIQGAAMAILVALYVSDFFKDTHSYKERKEED---PHTTLHETASSR 276

  Fly   253 NNST 256
            |.||
Mouse   277 NYST 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
laza	NP_649391.1	PAP2_wunen	62..217	CDD:239479	62/156 (40%)
Plpp1	NP_032273.1	PAP2_wunen	99..244	CDD:239479	62/156 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834748
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48083
OrthoDB	1	1.010	-	-		D434801at33208
OrthoFinder	1	1.000	-	-		FOG0000694
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.850