Protein Alignment laza and PLPPR5

DIOPT Version :10

• Sequence 1: NP_649391.1
• Gene: laza / 40468
• FlyBaseID: FBgn0037163
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_001032394.1
• Gene: PLPPR5 / 163404
• HGNCID: 31703
• Length: 321
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 81/298 - (27%)
• Similarity: 124/298 - (41%)
• Gaps: 60/298 - (20%)

  Fly     6 RGFFCSDLSIRYPY---KDCTITVPMLLLMMLL-LPMLFVAVVEIMRICKRFRTR---------- 56
            :||||.|.:.|.||   :|.:...|:||..:.. :|:|.:.|.|....|.:..||
Human    41 QGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTIL 105

  Fly    57 ----LYFRNLWRAEATF----SFGFIATYLTTELAKHAVGRLRPHFFHGCQPRLDDGSSCSDLQN 113
                .|...|.|....|    :||..||.:.....:...|.|.|||...|:|.. ....|.  |.
Human   106 TGDCCYINPLVRRTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLALCKPNY-TALGCQ--QY 167

  Fly   114 AELYVEQFHCTNNNLSTRQIRELHVSFPSAHSSLSFYSMVLLALYVHGVWRGRGGVRVLRHVLQF 178
            .:....:..||.|.....:.|:   :|||..::||.|:.:.|.:|:....:.: |.|:.:.||..
Human   168 TQFISGEEACTGNPDLIMRARK---TFPSKEAALSVYAAMYLTMYITNTIKAK-GTRLAKPVLCL 228

  Fly   179 LLLMAALCVSLSRVADYWHHWSDVLAGALLGVTYAA-ITAAYVGNLLRRQTSSTGRIPPSLNYSH 242
            .|:..|....|:|||:|.:|||||:||.|:|::.|. :....|.|...||..           :.
Human   229 GLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQAE-----------NE 282

  Fly   243 HLHHQLMAD-------------------NNNSTASAKV 261
            |:|...:|.                   .|:.||.|:|
Human   283 HIHMDNLAQMPMISIPRVESPLEKVTSVQNHITAFAEV 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
laza	NP_649391.1	PAP2_wunen	62..217	CDD:239479	49/159 (31%)
PLPPR5	NP_001032394.1	PAP2_wunen	118..267	CDD:239479	47/155 (30%)