DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment laza and plpp5

DIOPT Version :9

Sequence 1:	NP_649391.1	Gene:	laza / 40468	FlyBaseID:	FBgn0037163	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_001121478.1	Gene:	plpp5 / 100158576	XenbaseID:	XB-GENE-5812193	Length:	266	Species:	Xenopus tropicalis

Alignment Length:	229	Identity:	68/229 - (29%)
Similarity:	95/229 - (41%)	Gaps:	50/229 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHTFKRGFFCSDLSI-RYPY--KDCTITVPMLLLMMLLLPMLFVAVVEIMRICKRFRTRLYFRNL 62
            ||.|:|.....::.: |.||  .|...|..|.|: ..|.|:|.|.:..:               .
Frog    29 MHPFERLIQPEEMWLYRNPYVVSDRVPTNSMFLI-SFLTPLLVVVLARV---------------F 77

  Fly    63 WRAEAT--------FSFGFIATYLTTELAKHAVGRLRPHFFHGCQPRLDDGSSCSDLQNAELYVE 119
            |:|:.|        .|.......:.|...|..|||.||.|...|.|   ||...          .
Frog    78 WKADNTDAREAGLAASLSLALNGIFTNTVKLIVGRPRPDFLSRCFP---DGRES----------P 129

  Fly   120 QFHCTNNNLSTRQIRELHVSFPSAHSSLSFYSMVLLALYVHGVWR-----GRGGVRVLRHVLQFL 179
            :||||.:   ...:.|...||||.|:|.:|..:...|||:.|..|     |||  ...|.....:
Frog   130 EFHCTGD---PELVIEGRKSFPSGHASFAFAGLGFTALYLAGKLRCFSSYGRG--HSWRLCTSLI 189

  Fly   180 LLMAALCVSLSRVADYWHHWSDVLAGALLGVTYA 213
            .|:.|:.::|||..||.|||.||:.||.:|:.:|
Frog   190 PLLCAIAIALSRTCDYKHHWQDVVVGAFIGLFFA 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
laza	NP_649391.1	PAP2_wunen	62..217	CDD:239479	53/165 (32%)
plpp5	NP_001121478.1	PAP2_containing_1_like	42..230	CDD:239484	64/216 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1621899at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3374
SonicParanoid	1	1.000	-	-		X622
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040