Protein Alignment CG11449 and LOC4577402

DIOPT Version :10

• Sequence 1: NP_649390.1
• Gene: CG11449 / 40467
• FlyBaseID: FBgn0037162
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_001238576.4
• Gene: LOC4577402 / 4577402
• VectorBaseID: AGAMI1_000247
• Length: 539
• Species: Anopheles gambiae
• Alignment Length: 547
• Identity: 163/547 - (29%)
• Similarity: 313/547 - (57%)
• Gaps: 32/547 - (5%)

  Fly     1 MPCFSASNVRFVSAESQVQKKCNELRARARAQTAAYRPPACG-FHPTATSFGSFRRPL-CDQSAA 63
            ||..|..:..||.|::: ....|:|.|:      .:||.... .||.........||: ..:...
Mosquito     1 MPMQSKHSKNFVKAQAK-SNYSNDLPAK------QHRPGVYNRHHPQECDLMLRWRPIHLQRDDP 58

  Fly    64 YDQKQLKR-NERDRKRN---QGTKQVVLRA----GELRRLKDQGKLETVSEKLQRIEQHEEEHRK 120
            |:.|.:.: ..:|..||   ...:..|..|    .:..|::|:.||:|:.::|.:.:.:|.|.:.
Mosquito    59 YEGKNVVQIMNKDNVRNLLIPSKESSVYPAFWSKEDYERMQDKAKLKTLEDRLAQFKANETEKKN 123

  Fly   121 QLQMVEETRQRFKAIDEAKGVGASESRSTLLSEILEEKE----------SVLSRAFLARQEQEQE 175
            .|:..|..::|.:.||..:     :.:...:..|||:.|          .::.|||||:||||:|
Mosquito   124 MLEESERRKKRLQEIDRER-----QQKGGKVGNILEDGEGDRDSDTSPRKIIDRAFLAKQEQEEE 183

  Fly   176 VKQINRMILDAKCKAVREAQIHEKHLLSKALREDDERLARMVNERAQKALTEEDERERLEVEKRN 240
            ||:.||:||.|||..:|:|||.||..:.:.||.::.||.:|:.:..:|||.||:::..:......
Mosquito   184 VKRANRIILAAKCHIIRDAQIAEKQEIERELRTEELRLEKMMLQENEKALKEEEKKREVNKVLTT 248

  Fly   241 RYAQEIRQQLSERENVRYLEAKRVADEAKDIRRATELLRSQEEQQRAFAQLRKQRLREELQRIRD 305
            ::::|||.||.|||.:|..||:|:.:||:.:::|...:..:|:::......|..::||.|::..:
Mosquito   249 QHSEEIRNQLLEREKMRLKEAERIEEEARVLKQAQMAIAEEEKRKEKERHDRVNQVREGLKKAYE 313

  Fly   306 MSNVFKTMFSEQERLADLRVTAYMRDKQEKERQLKEMKRLAKKEFERRQQRIFTVAAEAMETRQT 370
            :|..:|.:..|::|:|:|::..|||.:.|::::::..:::|.:..|:...|:..:..:.::|:..
Mosquito   314 LSAHYKQVEFEEQRIAELKIQEYMRQRMERQKKIEFERKIAAEVREKEHDRMLKIQQKLLDTKSE 378

  Fly   371 NDELKYLKERDRVEREYRQREKEAAIARREAERDLLEARAQQAQEMKQRLALEIAHAGEEFAKVM 435
            .:::...:.::.:|||:|:|||||||.::|.|:.|..|||.|.:.:|...|:::|...:|..|.:
Mosquito   379 KNDMDLRRGQEHIEREFRRREKEAAIKKKELEQQLAVARAAQLEAVKTERAMQLARDEQEHKKAI 443

  Fly   436 DRMREEEEKQKVMDRQRDAQRQAYRQDLRQQMTDKQAERRRLAELEAGRVQKWLDHEKQRDVNIQ 500
            ::::.||.|:....|::...|:.||:::.|||..|:.|||....:.....|..|:.||:||.||:
Mosquito   444 EKLKVEEAKEMEQKRKQLKLRERYREEIIQQMNLKEQERREKERIAKNEQQALLEAEKKRDRNIK 508

  Fly   501 QVINAKIAAMRDNCLPEKYLREVEKQL 527
            .:|..||..|:::.:||:::::||:||
Mosquito   509 TIIANKIKMMKESQVPERFIKDVERQL 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11449	NP_649390.1	DUF5401	<70..>263	CDD:375164	68/210 (32%)
		TPH	169..507	CDD:464007	110/337 (33%)
LOC4577402	XP_001238576.4	None