Protein Alignment CG11449 and cfap45

DIOPT Version :10

• Sequence 1: NP_649390.1
• Gene: CG11449 / 40467
• FlyBaseID: FBgn0037162
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001076465.2
• Gene: cfap45 / 325276
• ZFINID: ZDB-GENE-070209-143
• Length: 543
• Species: Danio rerio
• Alignment Length: 576
• Identity: 145/576 - (25%)
• Similarity: 259/576 - (44%)
• Gaps: 88/576 - (15%)

  Fly     1 MPCFSASNVRFVSAESQVQKKCNELRARARAQTAAYRPPACGFHPTATSFGSFRRPLCDQSAAYD 65
            ||..:||:...:|..|              |.|..||..|...|...:.|||   |....:|...
Zfish     1 MPQSAASSSGKLSGGS--------------AFTRRYRTRALTSHVDESLFGS---PKLHSTADMR 48

  Fly    66 QKQLKRNERDRKRNQGT-------------------------------KQVVLRAGELRRLKDQG 99
            ......|||.|..:...                               :.|:|.:.|.||:..:.
Zfish    49 NHPEGENERTRSLSHSAPSSKEPKSETIRIITKDLIRDLRIPSEDPSGQSVILSSNEFRRIMAES 113

  Fly   100 KLETVSEKLQRIEQHEEEHRKQLQMVEETRQRFKAIDEAKGVGASESRSTLLSEILEEKESVLSR 164
            .:.:..||..|:|...:...:.:...|:.:.:.:..|.::  ..:::.|.|.:|..:..:.:|.|
Zfish   114 HVPSEEEKTARLEAQRQALEEAMDAAEQRKAQMRQADLSR--QKNQNLSELEAEARDRAQYLLER 176

  Fly   165 AFLARQEQEQEVKQINRMILDAKCKAVREAQIHEKHLLSKALREDDERLARMVNERAQKALTEED 229
            |...|.|||.|||::|.:|...:|.|||:.||.|:.|.|.....:::||..|:....::||..::
Zfish   177 ANTLRMEQEDEVKKLNELIQKVQCHAVRDVQIQERKLNSAEWLAEEKRLDAMMEVERRQALEAQE 241

  Fly   230 ERERLEVEKRNRYAQEIRQQLSERENVRYLEAKRVADEAKDIRRATELLRSQEEQQRAFAQLR-- 292
            :.|:|..::|.:....|..|:..|:     |.|.:.||.|: :...:||.:.|..|  ..:|:
Zfish   242 QIEQLRKQQRIQGKMCIIDQIQTRQ-----EEKLLQDEMKE-QEGQQLLENMERMQ--MEELKGI 298

  Fly   293 ------KQRLREELQRIRDMSNVFKTMFSEQERLADLRVTAYMRDKQEKERQLKEMKRLAKKEFE 351
                  :::|.:|:|:|.:.:.:.|....|:|||||||...|.|:|.|:|.:.:..:...||:.|
Zfish   299 EKKKEEQKKLLQEIQKINEENLLAKEQKKEEERLADLRAVEYTRNKLEREAEYEAEQIRIKKDKE 363

  Fly   352 RRQQRIFTVAAEAMETRQTNDELKYLKERDRVEREYRQREKEAAIARREAERDLLEARAQQAQEM 416
            :...|:..:.....:.:...||::..:.::...||:|::|||.|..:.|.|..|..||.:|....
Zfish   364 KEVARLRALQERDRDHKAEQDEIRARRNQEAAAREWRRKEKEQAKRKLEVEERLKAARLEQVTHK 428

  Fly   417 KQRLALEIAHAGEEFAKVMDRMRE--------EEEKQKVMDRQRDAQRQAYRQDLRQQMTDKQ-- 471
            :..|::|......||.:|:...:|        ||::|:.:.:..||.||..|:...|.:|.::
Zfish   429 EHLLSIEAGRERAEFERVLRAQQELIEREYEKEEQRQQQIQKHADAVRQQVREREMQAVTQRREM 493

  Fly   472 -AERRRLAELEAGRVQKWLDHEKQRDVNIQQVINAKIAAMRDNCLPEKYLREVEKQ 526
             .||.||.| ||          :.|...:.::...|:..::...|..||.:|||::
Zfish   494 FRERERLEE-EA----------RNRRARLDEIKEKKLKELKAAGLSPKYYKEVERK 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11449	NP_649390.1	DUF5401	<70..>263	CDD:375164	51/223 (23%)
		TPH	169..507	CDD:464007	100/356 (28%)
cfap45	NP_001076465.2	TPH	181..514	CDD:464007	100/351 (28%)