DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ten-m and C05B5.5

DIOPT Version :9

Sequence 1:NP_001262211.1 Gene:Ten-m / 40464 FlyBaseID:FBgn0004449 Length:3349 Species:Drosophila melanogaster
Sequence 2:NP_499219.3 Gene:C05B5.5 / 176413 WormBaseID:WBGene00007322 Length:337 Species:Caenorhabditis elegans


Alignment Length:344 Identity:71/344 - (20%)
Similarity:120/344 - (34%) Gaps:116/344 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly  2553 SSTHYTYQDTTSLVKSVEVQEPG--FELRREFK-YHAGILKDEKLRFGSKN-SLAS----ARYKY 2609
            ||.:|.....|...|..|...|.  |:|.|..| .|..|||::|  |..|: .|.:    .::::
 Worm    11 SSLNYVDLPDTVHRKIFEYLNPWEIFKLSRISKAIHVTILKNKK--FAVKDIDLCTDENILKFQF 73

  Fly  2610 AYDGNARLSGIEMAIDDKELPTTRYKYSQNLGQLEVVQDLK------------ITRNAFNRTVIQ 2662
            .:..|..||.....:.:|...|:::   .|..|.....|:|            ..|||.:...:|
 Worm    74 QFVNNIVLSWEFYNLHEKPYFTSQF---SNRCQYRQQYDIKNYYENPEEAFLFAFRNALSIFNVQ 135

  Fly  2663 DS-AKQF--------------FAIVDYDQHGRVKSVLMNVKNIDVFRL------ELDYDLR---- 2702
            :| .|:|              ::.:|    ||      |.:|:.::..      |.|:.:.    
 Worm   136 NSKLKRFYLAPSKLELFFKLPYSFID----GR------NCENLSIWNKKANDEDERDFSINFAKA 190

  Fly  2703 -----NRIKSQKTTFGRST---AFD--KINYNADGHVVEVLGTNNWKYLFDENGNTVGVVDQGEK 2757
                 ..:::.:..|..||   .||  |..||::   .:.|..|:| ||::              
 Worm   191 VLEKMGVVRNLRLLFNCSTKDNEFDCEKEYYNSE---TDKLMPNDW-YLYN-------------- 237

  Fly  2758 FNLGYDIGDRVIKVGDVEFNNYDARGFVVKRGEQKYRYNNRGQLIHSFE---RERFQSWYYYDDR 2819
                        |..|::.|.:           .|...|.|..||..|.   :..|.:...:|. 
 Worm   238 ------------KFDDIDLNVF-----------LKNWLNFRDPLIRKFRIRGKRNFNTAIIFDG- 278

  Fly  2820 SRLVAWHDNKGNTTQYYYA 2838
            ...:.| |.:.....|||:
 Worm   279 IETIPW-DQRNGLNVYYYS 296

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ten-mNP_001262211.1 TNFRSF 1069..1198 CDD:304602
CRD2 1106..1151 CDD:276900
EGF_2 1139..1162 CDD:285248
Keratin_B2 1162..1330 CDD:279797
EGF_2 1167..1194 CDD:285248
DUF3844 1171..>1235 CDD:289707
EGF_2 <1272..1294 CDD:285248
NHL 1750..2065 CDD:302697
NHL repeat 1784..1830 CDD:271320
NHL repeat 1854..1888 CDD:271320
NHL repeat 1911..1950 CDD:271320
NHL repeat 1972..2005 CDD:271320
NHL repeat 2039..2065 CDD:271320
RHS_repeat 2183..2218 CDD:283287
RhsA 2347..3020 CDD:225750 71/344 (21%)
YD_repeat_2x 2795..2836 CDD:273728 9/43 (21%)
Rhs_assc_core 2905..2980 CDD:274730
Tox-GHH 3193..3268 CDD:292269
C05B5.5NP_499219.3 FBOX 18..55 CDD:197608 13/38 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1225
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.