Protein Alignment Ten-m and WIF1

DIOPT Version :10

• Sequence 1: NP_001262211.1
• Gene: Ten-m / 40464
• FlyBaseID: FBgn0004449
• Length: 3349
• Species: Drosophila melanogaster
• Sequence 2: NP_009122.2
• Gene: WIF1 / 11197
• HGNCID: 18081
• Length: 379
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 70/231 - (30%)
• Similarity: 89/231 - (38%)
• Gaps: 53/231 - (22%)

  Fly  1045 VSLYNDDGDV-----QELTFYAAVAEDMTQNCPNGCSGNGQCLLGH-CQCNPGFGGDDCSESVCP 1103
            |.:.|.:|:.     |...|:....:   ..||.||...|.|.... |:|..||.|..|.:::|.
Human   154 VIVMNSEGNTILQTPQNAIFFKTCQQ---AECPGGCRNGGFCNERRICECPDGFHGPHCEKALCT 215

  Fly  1104 VLCSQHGE-YTNGECICNPGWKGKECSLRHDECEVADCSGHGHC-VSGKCQCMRGYKGKFCEEVD 1166
            ..|...|. .|.|.|||.||:.|..|...:  |... |...|.| ..|||.|..|.:|:.||...
Human   216 PRCMNGGLCVTPGFCICPPGFYGVNCDKAN--CSTT-CFNGGTCFYPGKCICPPGLEGEQCEISK 277

  Fly  1167 CPHPNCSGHGFCADGTCICKKGWKGPDCATMDQDALQCLPDCSGHGTFDLDTQTCTCEAKWSGDD 1231
            ||.|              |:.|.|                 |.|       ...|.|...:.||.
Human   278 CPQP--------------CRNGGK-----------------CIG-------KSKCKCSKGYQGDL 304

  Fly  1232 CSKELCDLDCGQHGRC-EGDACACDPEWGGEYCNTR 1266
            |||.:|:..||.||.| |.:.|.|...|.|.:||.|
Human   305 CSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ten-m	NP_001262211.1	EGF_Tenascin	1071..1098	CDD:480934	11/27 (41%)
		EGF_2	1139..1162	CDD:400365	9/23 (39%)
		DUF5885	<1181..1229	CDD:437064	7/47 (15%)
		EGF_2	1272..1294	CDD:400365
		acid_disulf_rpt	1337..1363	CDD:411265
		NHL	1750..2065	CDD:302697
		NHL repeat	1784..1830	CDD:271323
		NHL repeat	1854..1888	CDD:271323
		NHL repeat	1911..1950	CDD:271323
		NHL repeat	1972..2005	CDD:271323
		NHL repeat	2039..2065	CDD:271323
		RHS_repeat	2183..2217	CDD:461685
		RhsA	<2248..2980	CDD:442442
		Tox-GHH	3191..3268	CDD:464783
WIF1	NP_009122.2	WIF	35..179	CDD:128745	5/24 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	354..379