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Protein Alignment Ten-m and tnr

DIOPT Version :9

Sequence 1:	NP_001262211.1	Gene:	Ten-m / 40464	FlyBaseID:	FBgn0004449	Length:	3349	Species:	Drosophila melanogaster
Sequence 2:	NP_001107287.1	Gene:	tnr / 100135076	XenbaseID:	XB-GENE-948286	Length:	1350	Species:	Xenopus tropicalis

Alignment Length:	1446	Identity:	305/1446 - (21%)
Similarity:	471/1446 - (32%)	Gaps:	481/1446 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  1193 DCATMDQDA---LQCLPDCSGHGTFDLDTQTCTCEAKWSGDDCSKELCDLDCGQHGRCEGDACAC 1254
            |.|..|.:|   .:..|.|||||.|.:|  :|.|...|.|::||:.||.|:|...|.|....|.|
Frog   152 DRACQDAEATGLTEFAPPCSGHGNFTVD--SCICNQGWGGENCSEPLCPLECSGRGTCIEGMCVC 214

  Fly  1255 DPEWGGEYCNTRLCDVRCNEHGQCKNGTCLCVTGWNGKHCTIEGCPNSCAGHGQCRVSGEGQWEC 1319
            :|::.||:|...||...|:.||.|::|.|:|...:.|..||...||..|.|.|:|     ....|
Frog   215 EPDYTGEWCTDLLCPEECSPHGLCQDGQCVCQDPYIGIGCTELRCPGDCLGKGRC-----ANGTC 274

  Fly  1320 RCYEGWDGPDCGIALELNCGDSKDNDKDGLVDCEDPECCASHVCKTSQLCVSAPKPIDVLLRKQP 1384
            .|.:|:.|.|||....:|....:...:||:.:||:.        .:.|.|.....|:|
Frog   275 VCQDGYAGEDCGRMWCINACSGRGQCQDGVCECEEG--------YSGQDCSEVAPPVD------- 324

  Fly  1385 PAITASFFERMKFLIDESSLQNYAKLETFNESIFWNYFNASRSAVIRGRVVTSLGMGLVGVRVST 1449
                                                 |:           ||::|
Frog   325 -------------------------------------FS-----------VTAVG---------- 331

  Fly  1450 TTLLEGFTLTRDDGWFDLMVNGGGAVT-LQFGRAPFRP-----QSRIVQ-VP--WNEVVIIDLVV 1505
                        |.|.||...|..||| ......|..|     |.|:.| ||  |:.|.|.:|
Frog   332 ------------DHWMDLAWEGTTAVTEYVISYQPAVPGEWGTQQRLQQRVPGDWSSVTIREL-- 382

  Fly  1506 MSMSEEKGLAVTTTHTCFAHDYDLMKPVVLASWKHGFQGACPDRSAILAESQVIQESLQIPG-TG 1569
                 |.|:.           |::              ..|...|.|::|...|..|..|.. .|
Frog   383 -----EPGVT-----------YNI--------------SVCSVISDIISEPASITISTHISSPRG 417

  Fly  1570 LNLVYHSSRAAGYLSTIKLQLTPDVIPTSLHLIHLRITIEGILFERIFEADPGIKFTYAWNRLNI 1634
            ||.:..:.      :::::...|.|.|           ::|      :|    |.||...|...:
Frog   418 LNFMEVTQ------TSVEVHWDPPVFP-----------LDG------WE----ISFTPKNNEGGL 455

  Fly  1635 YRQRVYGVTT---AVVKVGYQYTDCTDIVWDIQTTKLSGHDMSISEVGGWNLDIHHRYNFHEGIL 1696
            ..|....||:   ..:|.|.:||        :....|.....|.:..|..:.||
Frog   456 TVQLPSSVTSFNQTGLKPGEEYT--------VSIISLKDQARSPATSGSISTDI----------- 501

  Fly  1697 QKGDG-SNIYLRNKPRIILTTMGDGHQRPLECPDCD-------GQATKQRLLAPVALAAAPDGSL 1753
               || :||.:|:....:........:..|:....|       |:.|..||..|::
Frog   502 ---DGPTNILVRDVTDTVAFVEWTPARAKLDFMQLDYGPINGEGEKTTFRLQPPLS--------- 554

  Fly  1754 FVGDFNYIRRIMTDGSIRTVVKLNATRVSYRYHMALSPLDGTLYVSDPESHQIIRVRDTNDYSQP 1818
                 .|..:::..||              :|.:::..:.|     |.|| :.:|...|.:...|
Frog   555 -----QYSMQVLRPGS--------------QYEISIRGVRG-----DTES-EPVRATFTTELDAP 594

  Fly  1819 -------------ELNWEAVVGSGE------RCLPGDEAHCGDGALAKDAKLAYPKGIAISSDNI 1864
                         ||.|:.....||      ..|.||:.|          :|..|:.
Frog   595 KNLRVISHASSTLELEWDNSEAEGEGYRVVYSTLAGDQYH----------ELIVPRN-------- 641

  Fly  1865 LYFADGTNIRMVDRDGIVSTLIGNHMHKSHWKPIPCEGTLKLEEMHLRWPTELAVS-PMDNTLHI 1928
              :...|...:.|........||....:.:.|..|.....:.|   |..||:|.|: ..|.::.:
Frog   642 --YGQTTKATLTDLIPGTEYGIGISAIRYNLKSAPATMNARTE---LDSPTDLMVTGSTDKSISL 701

  Fly  1929 I-------DDHMILRMTPDGRVRVISGRPLHCATASTAYDTDLATHATLVMPQSIAFGPLGELYV 1986
            .       .||..:..||.      ||               :|:..|  :|..|:...|.||..
Frog   702 TWTKARGPIDHYRISFTPS------SG---------------MASEVT--VPSDISQYELSELEP 743

  Fly  1987 AESDSQRINRVRVIGTDGRIAPFAGAESKCNCLERGCDCFEAEHYLATSAKFNTIAAL-AVTPDS 2050
                          ||:..|:.||         |||          ...:|..||.|. ...|.:
Frog   744 --------------GTEYTISIFA---------ERG----------RQQSKETTIDAFTGFRPIT 775

  Fly  2051 HVHIADQANYRIRSVMSSIPEASPSREYEIYAP----DMQEIYIFNRFGQHVSTR-NILTGETTY 2110
            .:|.:....|.: :|..:.|...|.:....|.|    |..::::.....|   || :.|...|.|
Frog   776 QLHFSAVTAYSV-NVSWTDPSPPPDQFILTYNPIDSKDPLQLFLDPSLRQ---TRLSALQPSTEY 836

  Fly  2111 VFTYNV--NTSNGKL--STVTDAAGNKVFLLRDYTSQVNSIENTKGQKCRLRMTRMKMLHELSTP 2171
            :.|...  .|...:|  .|||......:.|     |.:|..||:.....|   .....||
Frog   837 MVTLLPVHGTVRAELVEGTVTTGVAPPMDL-----SVINVTENSLAVVWR---PPPSSLH----- 888

  Fly  2172 DNYNVTYEYHGPTGLLRTKLDST----------------------------GR---------SYV 2199
             :|.:||:      ..:.::||.                            ||         |:.
Frog   889 -HYRLTYQ------STKGRMDSVVIGNDQTRYTLANLMPNTEYKISLRSVRGREESERVGIVSWT 946

  Fly  2200 YNYDEFGRLTSAVTPTGRVIELSFDLS-VKGAQVKVSENAQKEMSLLIQGATV--IVRNGAAESR 2261
            .....:|..||.:|.|..::......| |:...:.|:.:|....::|:.|.::  .::|....:.
Frog   947 AVDPPYGLRTSNITATEALLHWEPPRSEVESYVIIVTHHAGSGETILVDGESIEFQLQNLLPRTN 1011

  Fly  2262 TTVDMDGS-------------TTSITPWGHNLQMEVAPYTILAEQSPLLG--ESYPVPAKQRTEI 2311
            .:|.:..:             ||.:.|..:....|||..:.|....|.:.  |:|.:..|...|.
Frog  1012 YSVTLSANFGHQTSRSVGVSFTTILDPPMNLTATEVARTSALISWQPPISPIENYILTYKSANES 1076

  Fly  2312 AGDLANRFE--WRYFVRRQQPL------------QAGKQSKGPPRPVTEVGR---------KLRV 2353
            ..:|....|  |   :|.:..|            |.|::|.......|..||         :..:
Frog  1077 RKELIVDAEDTW---IRLEGLLESTEYTVSILSVQNGERSSVTHTVFTTGGRVFSYPQDCAQHML 1138

  Fly  2354 NGDNVLTLEY----DRETQSVVVMVDDKQELLNVTYDRTSRPISFRPQSG------DYADVDLEY 2408
            ||||...:.|    ...:|||.|..|       :..|.....:..|.|:|      .:||..:
Frog  1139 NGDNQSGVYYIYINGDMSQSVPVYCD-------MATDAGGWIVFQRRQNGLTDFFRKWADYRV-- 1194

  Fly  2409 DRFGRLVSWKWGVLQEAYSFDRNGRLN-EIKYGDGSTMVYAFKDMFGSLPLKVTTPRRSDYLLQY 2472
             .||.|....|..|...:.....||.. .|...||...|||:.:.|.      ....||.|.|:.
Frog  1195 -GFGNLEDEFWLGLDTLHQVTSQGRYELRIDMRDGQEAVYAYYNKFN------IGDARSLYKLRI 1252

  Fly  2473 DDAGAL--QSLTTPRG 2486
            .|....  .|||..:|
Frog  1253 GDFNGTSGDSLTYHQG 1268

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.