Protein Alignment Srpk79D and SRPK

DIOPT Version :10

• Sequence 1: NP_001246881.1
• Gene: Srpk79D / 40461
• FlyBaseID: FBgn0025702
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: NP_001369087.1
• Gene: SRPK / 36706
• FlyBaseID: FBgn0286813
• Length: 1009
• Species: Drosophila melanogaster
• Alignment Length: 738
• Identity: 279/738 - (37%)
• Similarity: 390/738 - (52%)
• Gaps: 117/738 - (15%)

  Fly   297 PRGTLSTTDEIYPDSSDSSLYVSDEEQEDASQYCRGGYHPVVIGDIFDNRFRVVRKLGWGHFSTV 361
            ||   |:::|.|    :|..:..:|:||....||:||||||.|||:|.:|:.|:|||||||||||
  Fly   127 PR---SSSNESY----ESETFSDNEDQELMEDYCKGGYHPVNIGDLFHDRYHVIRKLGWGHFSTV 184

  Fly   362 WLCRDLKDEKYVALKVVKSAPHYIETAADEIRLLEAIRDADPMDVKRERIVRLMNHFTVRGVNGM 426
            |||.||:...|||:|:||||||:.|||.|||::|:.:|:.||.:.:|.:.|::::.|.:.||||.
  Fly   185 WLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPRRHKTVQMLDDFKITGVNGT 249

  Fly   427 HTCLVFEALGCSLYKLIVKNNYQGLAIAQVRNIIRQVLEGLDYLHSKCSIIHTDIKPENILLVID 491
            |.|:|||.||.:|.|||.|:||:|:.:|.|:.|.|||||||||||:.|.||||||||||:||.:|
  Fly   250 HICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVD 314

  Fly   492 NAAAMNQQIDDEINSLRVKGVDFPDSYI--SSIEKQTKSRAKWPLIEPNGSTNTNTNTSNSTATN 554
                     :..:.||..:....   |.  |.:.....|||.....||..:...:.|........
  Fly   315 ---------EPHVRSLATEATQL---YCMNSKMYPSLVSRAPKEYREPPITGKMSKNRKKKLKKK 367

  Fly   555 SNSSTPLAAVIMSTLDKEDTTTTTSSTLNSNTTSSLASKYSSLLGDSECNGGLGGSANINNRYRT 619
            :.....|.......|::.|    ....:|.|...:                   |.|.|:
  Fly   368 AKKRMELFKQQRDYLEQAD----GQGAINPNEVQN-------------------GDAGIS----- 404

  Fly   620 EKKITAKSSGDCDEDAESDTLGEQSTLASTMDSPTDLDPEPELDSKPNTVPEPSEGPIPEQPTPN 684
                      |.||..:::::.:...:|:.       .|..:...:....||.||....:.|...
  Fly   405 ----------DADEYFDANSVEDNVHVAAG-------QPSRKQREERKAPPEQSEEAQEQDPLTE 452

  Fly   685 STNSSCPSHNTATIAKSKINSNILSTCTSLTSTNEYCFTNTNTTTASTPSAPP-------SATPS 742
            .|:.          ||.|....                 |.|.:..|....||       ||..|
  Fly   453 GTDK----------AKKKKKKK-----------------NKNKSNQSKGQQPPQLENSTSSAESS 490

  Fly   743 SAPALASATPPSTCTPSFTQIAPSATAPATST----TCTTSAEFYDGDHKTTSTSTTTTSNAISS 803
            ||.....|...::.|.:.:....|.|....|.    ......|....:|:..:.::...||:.|.
  Fly   491 SALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDSK 555

  Fly   804 ATTTTATTTTAIAKLNVHANAI------PSQNQSQSSQNNTYTIQSLIDNSNVRVKIADLGNACY 862
            .::.:...|:: |....|:|:.      |.|.:.::.::      ..:|..||.||||||||||:
  Fly   556 ISSGSVENTSS-ATNGPHSNSTLPTPPPPPQAKHKAKKD------PALDECNVHVKIADLGNACW 613

  Fly   863 DYHHFTEDIQTRQYRSIEVLLGAPYNYTADIWSTACLAFELATGDYLFDPHAGESYSRDEDHLAH 927
            ...|||||||||||||:||::||.||.:||||||||:.||||||||||:||:||||:||||||||
  Fly   614 VDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGESYTRDEDHLAH 678

  Fly   928 IVELLGSIPQSVIFRGKHGLKYFTSYGSLRNITKLKPWSLMNVLVEKYDWDPVEAKKFSDFLLPM 992
            |:||||.||:.::..|.:..|.||....||||:.||||.||:||:|||:|...:|..|:.||.||
  Fly   679 IIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPM 743

  Fly   993 LEYNPVIRASAAECLQHPWLEQE 1015
            ||::|..||:||||||||||..:
  Fly   744 LEFDPNKRATAAECLQHPWLRXD 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srpk79D	NP_001246881.1	Protein Kinases, catalytic domain	336..>504	CDD:473864	94/167 (56%)
		PHA03307	627..>759	CDD:223039	26/138 (19%)
		Protein Kinases, catalytic domain	<844..1012	CDD:473864	110/167 (66%)
SRPK	NP_001369087.1	Protein Kinases, catalytic domain	159..>318	CDD:473864	94/167 (56%)
		Protein Kinases, catalytic domain	<600..763	CDD:473864	109/162 (67%)