Protein Alignment Srpk79D and Dyrk2

DIOPT Version :9

• Sequence 1: NP_001246881.1
• Gene: Srpk79D / 40461
• FlyBaseID: FBgn0025702
• Length: 1018
• Species: Drosophila melanogaster
• Sequence 2: XP_006241453.2
• Gene: Dyrk2 / 314862
• RGDID: 1312039
• Length: 600
• Species: Rattus norvegicus
• Alignment Length: 975
• Identity: 177/975 - (18%)
• Similarity: 255/975 - (26%)
• Gaps: 539/975 - (55%)

  Fly   139 LSRAPAYTHGIPYPHFHGTQPAA----TTPHHLHLHHHGNGTAAGS-GSGVGSGPGS-------- 190
            |:|.|:......||...|...|.    .:|          |..||: .||||:||.|
  Rat     2 LTRKPSAAAPAAYPTGRGGDTAVRQLQASP----------GIGAGAPRSGVGTGPPSPIALPPLR 56

  Fly   191 GSGA--------GG--------------------------------LYQQPLSLASM-TAALPLA 214
            .|.|        ||                                |..||..|.:: ...||:.
  Rat    57 ASNATTTSHTIGGGKHTMNDHLHISHSHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLPVV 121

  Fly   215 P---------LYGSPLSL------------PLTSSQSTTKLSYRDDFLQQIGYLPTTRIYSTPTS 258
            |         ..||..||            |:|..|:..:      ::|::.......|:|.|..
  Rat   122 PERQLESIHRRQGSSTSLKSMEGMGKVKASPMTPEQAMKQ------YIQKLTAFEHHEIFSYPEI 180

  Fly   259 IVDEDKAQQDFLSLSLSPPLNRRRDMPALRGPFVSLSEPRGTLSTTDEIYPDSSDSSLYVSDEEQ 323
            ..             |.|...:|:.|..  ||             .:..|.|  |...||  :..
  Rat   181 YF-------------LGPNAKKRQGMTG--GP-------------NNGGYDD--DQGSYV--QVP 213

  Fly   324 EDASQYCRGGYHPVVIGDIFDNRFRVVRKLGWGHFSTVWLCRDLKDEKYVALKVVKSAPHYIETA 388
            .|...|                |:.|::.:|.|.|..|....|.|..::||||:|::...:...|
  Rat   214 HDHVAY----------------RYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQA 262

  Fly   389 ADEIRLLEAIRDADPMDVKRERIVRLMNHFTVRGVNGMHTCLVFEALGCSLYKLIVKNNYQGLAI 453
            |:|||:||.:|..|..:..  .::.::.:||.|.    |.|:.||.|..:||:||.||.:||.::
  Rat   263 AEEIRILEHLRKQDKDNTM--NVIHMLENFTFRN----HICMTFELLSMNLYELIKKNKFQGFSL 321

  Fly   454 AQVRNIIRQVLEGLDYLHSKCSIIHTDIKPENILLVIDNAAAMNQQIDDEINSLRVKGVDFPDSY 518
            ..||.....:|:.||.|| |..|||.|:|||||||
  Rat   322 PLVRKFAHSILQCLDALH-KNRIIHCDLKPENILL------------------------------ 355

  Fly   519 ISSIEKQTKSRAKWPLIEPNGSTNTNTNTSNSTATNSNSSTPLAAVIMSTLDKEDTTTTTSSTLN 583
                                                                             
  Rat   356 ----------------------------------------------------------------- 355

  Fly   584 SNTTSSLASKYSSLLGDSECNGGLGGSANINNRYRTEKKITAKSSGDCDEDAESDTLGEQSTLAS 648
                                                                             
  Rat   356 ----------------------------------------------------------------- 355

  Fly   649 TMDSPTDLDPEPELDSKPNTVPEPSEGPIPEQPTPNSTNSSCPSHNTATIAKSKINSNILSTCTS 713
                                                                             
  Rat   356 ----------------------------------------------------------------- 355

  Fly   714 LTSTNEYCFTNTNTTTASTPSAPPSATPSSAPALASATPPSTCTPSFTQIAPSATAPATSTTCTT 778
                                                                             
  Rat   356 ----------------------------------------------------------------- 355

  Fly   779 SAEFYDGDHKTTSTSTTTTSNAISSATTTTATTTTAIAKLNVHANAIPSQNQSQSSQNNTYTIQS 843
                                                             :.|.:||
  Rat   356 -------------------------------------------------KQQGRSS--------- 362

  Fly   844 LIDNSNVRVKIADLGNACYDYHHFTEDIQTRQYRSIEVLLGAPYNYTADIWSTACLAFELATGDY 908
                    :|:.|.|::||::......||:|.||:.||:|||.|....|:||..|:..||.|| |
  Rat   363 --------IKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTG-Y 418

  Fly   909 LFDPHAGESYSRDE-DHLAHIVELLGSIPQSVIFRGKHGLKYFTSYGSLR--NITKLKPWSLMNV 970
            ...|  ||    || |.||.::||||...|.::...|....:.:|.|..|  .:|.|...|:  |
  Rat   419 PLLP--GE----DEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSV--V 475

  Fly   971 L-------------VEKYDW--------DPVEAKKFSDFLLPMLEYNPVIRASAAECLQHPWLEQ 1014
            |             .|..:|        ||:    |.|||...||::|.:|.:..:.|:||||.:
  Rat   476 LNGGRSRRGKLRGPPESREWGNALKGCDDPL----FLDFLKQCLEWDPAVRMTPGQALRHPWLRR 536

  Fly  1015  1014
              Rat   537  536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srpk79D	NP_001246881.1	STKc_SRPK	336..>504	CDD:271038	57/167 (34%)
		S_TKc	347..>492	CDD:214567	56/144 (39%)
		STKc_SRPK	<844..1012	CDD:271038	62/191 (32%)
Dyrk2	XP_006241453.2	PKc_DYRK2_3	155..534	CDD:271126	140/808 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910